Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant mouse Macrophage Inflammatory Protein 1 alpha / CCL3 (ab9928)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant mouse Macrophage Inflammatory Protein 1 alpha / CCL3
    See all Macrophage Inflammatory Protein 1 alpha / CCL3 proteins and peptides

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Predicted molecular weight

      10 kDa

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab9928 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Lyophilized

      • Additional notes

        The biological activity of this product is determined by its ability to chemoattract mouse Balb/c peripheral blood MNCs and mouse Balb/c splenocytes using a concentration range of 10.0-100.0 ng/ml
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        Please reconstitute this product in 100ul sterile water.

      General Info

      • Alternative names

        • C C motif chemokine 3
        • CCL 3
        • CCL3
        • CCL3_HUMAN
        • Chemokine (C C motif) ligand 3
        • Chemokine C C motif ligand 3
        • Chemokine ligand 3
        • G0/G1 switch regulatory protein 19 1
        • G0/G1 switch regulatory protein 19-1
        • G0S19 1
        • G0S19 1 protein
        • Heparin binding chemotaxis protein
        • L2G25B
        • LD78 alpha
        • LD78-alpha(4-69)
        • LD78alpha
        • Macrophage inflammatory protein 1 alpha
        • Macrophage inflammatory protein 1-alpha
        • macrophage inflammatory protein 1a
        • MIP 1 alpha
        • MIP 1A
        • MIP-1-alpha
        • MIP-1-alpha(4-69)
        • MIP1 alpha
        • MIP1A
        • PAT 464.1
        • SCYA 3
        • SCYA3
        • SIS alpha
        • SIS beta
        • SIS-beta
        • Small inducible cytokine A3
        • small inducible cytokine A3 (homologous to mouse Mip-1a)
        • Small-inducible cytokine A3
        • Tonsillar lymphocyte LD78 alpha protein
        see all

      • Function

        Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

      • Sequence similarities

        Belongs to the intercrine beta (chemokine CC) family.

      • Post-translational
        modifications

        N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab9928? Please let us know so that we can cite the reference in this datasheet.

    ab9928 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • C C motif chemokine 3
      • CCL 3
      • CCL3
      • CCL3_HUMAN
      • Chemokine (C C motif) ligand 3
      • Chemokine C C motif ligand 3
      • Chemokine ligand 3
      • G0/G1 switch regulatory protein 19 1
      • G0/G1 switch regulatory protein 19-1
      • G0S19 1
      • G0S19 1 protein
      • Heparin binding chemotaxis protein
      • L2G25B
      • LD78 alpha
      • LD78-alpha(4-69)
      • LD78alpha
      • Macrophage inflammatory protein 1 alpha
      • Macrophage inflammatory protein 1-alpha
      • macrophage inflammatory protein 1a
      • MIP 1 alpha
      • MIP 1A
      • MIP-1-alpha
      • MIP-1-alpha(4-69)
      • MIP1 alpha
      • MIP1A
      • PAT 464.1
      • SCYA 3
      • SCYA3
      • SIS alpha
      • SIS beta
      • SIS-beta
      • Small inducible cytokine A3
      • small inducible cytokine A3 (homologous to mouse Mip-1a)
      • Small-inducible cytokine A3
      • Tonsillar lymphocyte LD78 alpha protein
      see all

    • Function

      Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).

    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.

    • Post-translational
      modifications

      N-terminal processed form LD78-alpha(4-69) is produced by proteolytic cleavage after secretion from HTLV1-transformed T-cells.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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