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Recombinant Mouse LYVE1 protein (Fc Chimera) (ab214558)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: >= 98% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Mouse LYVE1 protein (Fc Chimera)
    See all LYVE1 proteins and peptides

  • Purity

    >= 98 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    Q8BHC0

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Mouse

    • Sequence

      ADLVQDLSISTCRIMGVALVGRNKNPQMNFTEANEACKMLGLTLASRDQV ESAQKSGFETCSYGWVGEQFSVIPRIFSNPRCGKNGKGVLIWNAPSSQKF KAYCHNSSDTWVNSCIPEIVTTFYPVLDTQTPATEFSVSSSAYLASSPDS TTPVSATTRAPPLTSMARKTKKICITEVYTEPITMATETEAFVASGAAFK NEAAG

    • Predicted molecular weight

      35 kDa

    • Amino acids

      24 to 228

    • Additional sequence information

      Recombinant fragment fused to the N-terminus of the Fc region of mouse IgG2a.

    • Specifications

    Our Abpromise guarantee covers the use of ab214558 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at -20°C long term. Avoid freeze / thaw cycle.

      Constituent: 100% PBS

    • Reconstitution
      Reconstitute with 50 µL sterile water. Add 1X PBS to the desired protein concentration. Working aliquots are stable for up to 3 months when stored at -20°C.

    General Info

    • Alternative names

      • Cell surface retention sequence-binding protein 1
      • CRSBP 1
      • CRSBP-1
      • CRSBP1
      • extracellular link domain containing 1
      • extracellular link domain-containing 1
      • Extracellular link domain-containing protein 1
      • HAR
      • Hyaluronic acid receptor
      • Lymphatic endothelium specific hyaluronan receptor
      • lymphatic vessel endothelial hyaluronan receptor 1
      • Lymphatic vessel endothelial hyaluronic acid receptor 1
      • LYVE 1
      • LYVE-1
      • LYVE1
      • LYVE1_HUMAN
      • XLKD1
      see all

    • Function

      Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.

    • Tissue specificity

      Mainly expressed in endothelial cells lining lymphatic vessels.

    • Sequence similarities

      Contains 1 Link domain.

    • Post-translational
      modifications

      O-glycosylated.

    • Cellular localization

      Membrane. Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab214558? Please let us know so that we can cite the reference in this datasheet.

ab214558 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Cell surface retention sequence-binding protein 1
  • CRSBP 1
  • CRSBP-1

Images

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