Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Expression system: Escherichia coli
Purity: > 95% SDS-PAGE
Suitable for: SDS-PAGE, HPLC

Product name

Recombinant Mouse LIF protein
See all LIF proteins and peptides
Purity

> 95 % SDS-PAGE.
ab123757 is purified by proprietary chromatographic techniques. Purity is greater than 95% as determined by HPLC and SDS-PAGE.
Expression system

Escherichia coli
Accession

P09056
Protein length

Full length protein
Animal free

No
Nature

Recombinant
- Species
  
  Mouse
- Sequence
  
  MSPLPITPVNATCAIRHPCHGNLMNQIKNQLAQLNGSANALFISYYTAQG EPFPNNVEKLCAPNMTDFPSFHGNGTEKTKLVELYRMVAYLSASLTNITR DQKVLNPTAVSLQVKLNATIDVMRGLLSNVLCRLCNKYRVGHVDVPPVPD HSDKEAFQRKKLGCQLLGTYKQVISVVVQAF
- Predicted molecular weight
  
  20 kDa
- Amino acids
  
  24 to 203

Alternative names
- CDF
- Cholinergic Differentiation Factor
- D factor
- DIA
- Differentiation inducing factor
- differentiation inhibitory activity
- Differentiation stimulating factor
- Differentiation-stimulating factor
- Emfilermin
- Hepatocyte stimulating factor III
- HILDA
- Human interleukin in DA cells
- Leukemia inhibitory factor
- LIF
- LIF_HUMAN
- Melanoma derived LPL inhibitor
- Melanoma-derived LPL inhibitor
- MLPLI
see all
Function

LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.
Sequence similarities

Belongs to the LIF/OSM family.
Cellular localization

Secreted.
Target information above from: UniProt accession P15018 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

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