Recombinant Mouse Leptin protein (Animal Free) (ab217478)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Suitable for: SDS-PAGE, HPLC
-
Product name
Recombinant Mouse Leptin protein (Animal Free)
See all Leptin proteins and peptides -
Purity
> 98 % SDS-PAGE.
ab217478 is greater than 98% pure as assessed by SDS-PAGE gel and HPLC analyses. -
Expression system
Escherichia coli -
Accession
-
Protein length
Full length protein -
Animal free
Yes -
Nature
Recombinant -
-
Species
Mouse -
Sequence
MVPIQKVQDD TKTLIKTIVT RINDISHTQS VSAKQRVTGL DFIPGLHPIL SLSKMDQTLA VYQQVLTSLP SQNVLQIAND LENLRDLLHL LAFSKSCSLP QTSGLQKPES LDGVLEASLY STEVVALSRL QGSLQDILQQ LDVSPEC -
Predicted molecular weight
16 kDa -
Amino acids
22 to 167 -
Additional sequence information
Full length mature protein without the signal peptide.
-
Preparation and Storage
-
Alternative names
- FLJ94114
- LEP
- LEP_HUMAN
see all -
Function
May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass. -
Involvement in disease
Defects in LEP may be a cause of obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat. -
Sequence similarities
Belongs to the leptin family. -
Cellular localization
Secreted. - Information by UniProt
