Antibodies, Proteins, Kits and Reagents for Life Science

Recombinant Mouse IL-5RA protein (ab222449)

Key features and details

Expression system: Baculovirus infected insect cells
Purity: > 90% SDS-PAGE
Endotoxin level:
Tags: His tag C-Terminus
Suitable for: SDS-PAGE

Product name

Recombinant Mouse IL-5RA protein
See all IL-5RA proteins and peptides
Purity

> 90 % SDS-PAGE.
Endotoxin level
Expression system

Baculovirus infected insect cells
Accession

P21183
Protein length

Protein fragment
Animal free

No
Nature

Recombinant
- Species
  
  Mouse
- Sequence
  
  DLLNHKKFLLLPPVNFTIKATGLAQVLLHWDPNPDQEQRHVDLEYHVKIN APQEDEYDTRKTESKCVTPLHEGFAASVRTILKSSHTTLASSWVSAELKA PPGSPGTSVTNLTCTTHTVVSSHTHLRPYQVSLRCTWLVGKDAPEDTQYF LYYRFGVLTEKCQEYSRDALNRNTACWFPRTFINSKGFEQLAVHINGSSK RAAIKPFDQLFSPLAIDQVNPPRNVTVEIESNSLYIQWEKPLSAFPDHCF NYELKIYNTKNGHIQKEKLIANKFISKIDDVSTYSIQVRAAVSSPCRMPG RWGEWSQPIYVGKERKSLVEWHLEHHHHHH
- Predicted molecular weight
  
  38 kDa
- Amino acids
  
  18 to 340
- Tags
  
  His tag C-Terminus

Our Abpromise guarantee covers the use of ab222449 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Applications

SDS-PAGE
Form

Liquid
Concentration information loading...

Stability and Storage

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

pH: 7.40
Constituents: 10% Glycerol (glycerin, glycerine), PBS

Alternative names
- CD125
- CD125 antigen
- CDw125
- HSIL5R3
- IL-5 receptor subunit alpha
- IL-5R subunit alpha
- IL-5R-alpha
- IL-5RA
- IL5R
- IL5RA
- IL5RA_HUMAN
- Interleukin 5 Receptor alpha
- Interleukin 5 Receptor alpha chain
- Interleukin 5 receptor alpha subunit
- Interleukin 5 receptor subunit alpha
- Interleukin 5 receptor type 3
- Interleukin-5 receptor subunit alpha
- MGC26560
see all
Function

This is the receptor for interleukin-5. The alpha chain binds to IL5.
Tissue specificity

Expressed on eosinophils and basophils.
Sequence similarities

Belongs to the type I cytokine receptor family. Type 5 subfamily.
Domain

The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation.
Cellular localization

Membrane.
Target information above from: UniProt accession Q01344 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

SDS-PAGE - Recombinant Mouse IL-5RA protein (ab222449)

3 μg ab222449 analyzed by 15% SDS-PAGE.

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols