Recombinant Mouse IL-34 protein (ab184584)
Key features and details
- Expression system: Yeast
- Suitable for: SDS-PAGE
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Product name
Recombinant Mouse IL-34 protein
See all IL-34 proteins and peptides -
Expression system
Yeast -
Accession
-
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Mouse -
Sequence
NENLEIWTLTQDKECDLTGYLRGKLQYKNRLQYMKHYFPINYRIAVPYEG VLRVANITRLQKAHVSERELRYLWVLVSLNATESVMDVLLEGHPSWKYLQ EVQTLLENVQRSLMDVEIGPHVEAVLSLLSTPGLSLKLVRPKALLDNCFR VMELLYCSCCKQSPILKWQDCELPRLHPHSPGSLMQCTATNVYPLSRQTP TSLPGSPSSSHGSLP -
Predicted molecular weight
25 kDa -
Amino acids
21 to 235 -
Additional sequence information
Mature protein.
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Preparation and Storage
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Alternative names
- C16orf77
- Chromosome 16 open reading frame 77
- FPT025
see all -
Function
Cytokine that promotes the differentiation and viability of monocytes and macrophages. Stimulates phosphorylation of MAPK1/ERK2 AND MAPK3/ERK1. Ligand for colony-stimulating factor-1 receptor CSF1R. -
Tissue specificity
Detected in the sinusoidal epithelium in the red pulp of spleen (at protein level). Predominantly expressed in spleen. Also detected in a range of other tissues including heart, brain, lung, liver, kidney, thymus, testis, ovary, small intestine, prostate and colon. -
Sequence similarities
Belongs to the IL-34 family. -
Cellular localization
Secreted. - Information by UniProt