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Signal Transduction Growth Factors/Hormones Hormones

Recombinant mouse Follistatin protein (Active) (ab269229)

Recombinant mouse Follistatin protein (Active) (ab269229)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

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Description

  • Product name

    Recombinant mouse Follistatin protein (Active)
    See all Follistatin proteins and peptides
  • Biological activity

    MCP-11 cell proliferation (typical ED50

  • Purity

    >90% by SDS-PAGE.

  • Endotoxin level

  • Expression system

    Escherichia coli
  • Accession

    P47931
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      MGNCWLRQAK NGRCQVLYKT ELSKEECCST GRLSTSWTEE DVNDNTLFKW MIFNGGAPNC IPCKETCENV DCGPGKKCRM NKKNKPRCVC APDCSNITWK GPVCGLDGKT YRNECALLKA RCKEQPELEV QYQGKCKKTC RDVFCPGSST CVVDQTNNAY CVTCNRICPE PSSSEQYLCG NDGVTYSSAC HLRKATCLLG RSIGLAYEGK CIKAKSCEDI QCGGGKKCLW DSKVGRGRCS LCDELCPDSK SDEPVCASDN ATYASECAMK EAACSSGVLL EVKHSGSCN
    • Predicted molecular weight

      38 kDa
    • Amino acids

      30 to 317
  • Specifications

    Our Abpromise guarantee covers the use of ab269229 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C..

      Constituents: 0.16% Sodium phosphate, 0.29% Sodium chloride

      Lyophilized from

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      Sterile water at 0.1 mg/mL

    General Info

    • Alternative names

      • Activin binding protein
      • Activin-binding protein
      • Follistatin
      • FS
      • fst
      • FST_HUMAN
      • Human follistatin gene
      see all
    • Function

      Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
    • Tissue specificity

      Isoform 1 is the predominant isoform in serum but is undetectable in follicular fluid.
    • Sequence similarities

      Contains 3 follistatin-like domains.
      Contains 3 Kazal-like domains.
      Contains 1 TB (TGF-beta binding) domain.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession P19883 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Images

  • SDS-PAGE - Recombinant mouse Follistatin protein (Active) (ab269229)
    SDS-PAGE - Recombinant mouse Follistatin protein (Active) (ab269229)
    SDS-PAGE analysis of ab269229 at 1ug/lane under (-) non-reducing and (+) reducing conditions. 4-20% Tris glycine gel. Stained with coomassie blue.

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
    • SDS
  • References (0)

    Publishing research using ab269229? Please let us know so that we can cite the reference in this datasheet.

    ab269229 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Activin binding protein
    • Activin-binding protein
    • Follistatin

    Images

    • SDS-PAGE - Recombinant mouse Follistatin protein (Active) (ab269229)
      SDS-PAGE - Recombinant mouse Follistatin protein (Active) (ab269229)
      SDS-PAGE analysis of ab269229 at 1ug/lane under (-) non-reducing and (+) reducing conditions. 4-20% Tris glycine gel. Stained with coomassie blue.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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