Recombinant mouse EPO protein (Fc Chimera) (ab170076)
Key features and details
- Expression system: Insect cells
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies
-
Product name
Recombinant mouse EPO protein (Fc Chimera)
See all EPO proteins and peptides -
Biological activity
ED50
-
Purity
> 95 % SDS-PAGE.
ab170076 is purified by chromatography, sterile filtered and lyophilized. -
Expression system
Insect cells -
Accession
-
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
-
Species
Mouse -
Sequence
APPRLICDSRVLERYILEAKEAENVTMGCAEGPRLSENITVPDTKVNFYA WKRMEVEEQAIEVWQGLSLLSEAILQAQALLANSSQPPETLQLHIDKAIS GLRSLTSLLRVLGAQKELMSPPDTTPPAPLRTLTVDTFCKLFRVYANFLR GKLKLYTGEVCRRGDR -
Predicted molecular weight
49 kDa -
Amino acids
27 to 192
-
Preparation and Storage
-
Alternative names
- EP
- EPO
- EPO alpha
see all -
Relevance
Human erythropoietin is member of the EPO/TPO family and encodes a secreted, glycosylated cytokine hormone composed of four alpha helical bundles. The protein is found in the plasma and regulates red cell production by promoting erythroid differentiation and initiating hemoglobin synthesis. This protein also has neuroprotective activity against a variety of potential brain injuries and antiapoptotic functions in several tissue types. It is produced by kidney or liver of adult mammals and by liver of fetal or neonatal mammals. -
Cellular localization
Secreted
Images
-
SDS-PAGE - Recombinant mouse EPO protein (Fc Chimera) (ab170076)SDS-PAGE analysis of ab170076.
Lane 1: 3µg ab170076 Reduced
Lane 2: 3µg ab170076 Non-reduced
Lane 3: Molecular weight markers -
Functional Studies - Recombinant mouse EPO protein (Fc Chimera) (ab170076)Proliferation of Human TF-1 erythroleukemia cells by ab170076.
