Recombinant Mouse CD209 protein (His tag) (ab276856)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 95% SDS-PAGE
- Endotoxin level:
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
-
Product name
Recombinant Mouse CD209 protein (His tag) -
Purity
> 95 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Protein fragmentAnimal free
NoNature
Recombinant-
Species
Mouse -
Sequence
QVSKTPNTER QKEQEKILQE LTQLTDELTS RIPISQGKNE SMQAKITEQ LMQLKTELLS RIPIFQGQNE SIQEKISEQL MQLKAELLSK ISSFPVKDDS KQEKIYQQL VQMKTELFRL CRLCPWDWTF LLGNCYFFSK SQRNWNDAVT ACKEVKAQLV IINSDEEQT FLQQTSKAKG PTWMGLSDLK KEATWLWVDG STLSSRFQKY WNRGEPNNIG EEDCVEFAGD GWNDSKCEL KKFWICKKSA TPCTEG -
Predicted molecular weight
31 kDa including tags -
Molecular weight information
The recombinant mouse CD209B comprises 268 amino acids and predicts a molecular mass of 31.4 kDa. As a result of glycosylation, the apparent molecular mass of mouse CD209B is approximately 40 kDa in SDS-PAGE under reducing conditions. -
Amino acids
74 to 325 -
Tags
His tag N-Terminus -
Additional sequence information
Predicted N-terminus: His.
Specifications
Our Abpromise guarantee covers the use of ab276856 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
Applications
SDS-PAGE
-
Form
Lyophilized -
Concentration information loading...
Preparation and Storage
-
Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
-
Alternative names
- CD209 antigen like protein B
- CD209b antigen
- DC SIGN related protein 1
see all -
Relevance
SIGN R1 is a specific marker for the identification of macrophage subpopulations present in the marginal zone of spleen (the so-called marginal zone macrophages (MZM)), in the lymph node medulla, and in some strains, in the peritoneal cavity. MZM of the spleen are involved in the clearance of polysaccharides. Mouse SIGN R1 is a C type lectin, like DC SIGN which is expressed on Human dendritic cells (DCs). However, Mmouse SIGN R1 itself is not expressed on DCs. SIGN R1 exists in an aggregated form, resistant to dissociation into monomers upon boiling in SDS under reducing conditions. SIGN R1 mediates the uptake of encapsulated organisms and may be an important mediator for the uptake of microbes in both spleen and lymph node, particularly through the recognition of microbial polysaccharides. -
Cellular localization
Single-pass type II membrane protein
Images
-
SDS-PAGE - Recombinant Mouse CD209 protein (ab276856)SDS-PAGE analysis of ab276856
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276856 has not yet been referenced specifically in any publications.
Preparation and Storage
- CD209 antigen like protein B
- CD209b antigen
- DC SIGN related protein 1
Images
-
SDS-PAGE - Recombinant Mouse CD209 protein (ab276856)SDS-PAGE analysis of ab276856