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Immunology Innate Immunity Macrophage / Inflamm.

Recombinant Mouse CD209 protein (His tag) (ab276856)

Recombinant Mouse CD209 protein (His tag) (ab276856)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag N-Terminus
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Mouse CD209 protein (His tag)
  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells
  • Accession

    Q8CJ91
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Mouse
    • Sequence

      QVSKTPNTER QKEQEKILQE LTQLTDELTS RIPISQGKNE SMQAKITEQ LMQLKTELLS RIPIFQGQNE SIQEKISEQL MQLKAELLSK ISSFPVKDDS KQEKIYQQL VQMKTELFRL CRLCPWDWTF LLGNCYFFSK SQRNWNDAVT ACKEVKAQLV IINSDEEQT FLQQTSKAKG PTWMGLSDLK KEATWLWVDG STLSSRFQKY WNRGEPNNIG EEDCVEFAGD GWNDSKCEL KKFWICKKSA TPCTEG
    • Predicted molecular weight

      31 kDa including tags
    • Molecular weight information

      The recombinant mouse CD209B comprises 268 amino acids and predicts a molecular mass of 31.4 kDa. As a result of glycosylation, the apparent molecular mass of mouse CD209B is approximately 40 kDa in SDS-PAGE under reducing conditions.
    • Amino acids

      74 to 325
    • Tags

      His tag N-Terminus
    • Additional sequence information

      Predicted N-terminus: His.
  • Specifications

    Our Abpromise guarantee covers the use of ab276856 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • CD209 antigen like protein B
      • CD209b antigen
      • DC SIGN related protein 1
      • DC SIGNR1
      • OtB7
      see all
    • Relevance

      SIGN R1 is a specific marker for the identification of macrophage subpopulations present in the marginal zone of spleen (the so-called marginal zone macrophages (MZM)), in the lymph node medulla, and in some strains, in the peritoneal cavity. MZM of the spleen are involved in the clearance of polysaccharides. Mouse SIGN R1 is a C type lectin, like DC SIGN which is expressed on Human dendritic cells (DCs). However, Mmouse SIGN R1 itself is not expressed on DCs. SIGN R1 exists in an aggregated form, resistant to dissociation into monomers upon boiling in SDS under reducing conditions. SIGN R1 mediates the uptake of encapsulated organisms and may be an important mediator for the uptake of microbes in both spleen and lymph node, particularly through the recognition of microbial polysaccharides.
    • Cellular localization

      Single-pass type II membrane protein

Images

  • SDS-PAGE - Recombinant Mouse CD209 protein (ab276856)
    SDS-PAGE - Recombinant Mouse CD209 protein (ab276856)
    SDS-PAGE analysis of ab276856

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab276856? Please let us know so that we can cite the reference in this datasheet.

    ab276856 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • CD209 antigen like protein B
    • CD209b antigen
    • DC SIGN related protein 1

    Images

    • SDS-PAGE - Recombinant Mouse CD209 protein (ab276856)
      SDS-PAGE - Recombinant Mouse CD209 protein (ab276856)
      SDS-PAGE analysis of ab276856

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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