Recombinant Human WISP1 protein (His tag) (ab276270)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 90% SDS-PAGE
- Endotoxin level:
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human WISP1 protein (His tag)
See all WISP1 proteins and peptides -
Purity
> 90 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Full length proteinAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
MRWFLPWTLA AVTAAAASTV LATALSPAPT TMDFTPAPLE DTSSRPQFCK WPCECPPSPP RCPLGVSLIT DGCECCKMCA QQLGDNCTEA AICDPHRGLY CDYSGDRPRY AIGVCAQVVG VGCVLDGVRY NNGQSFQPNC KYNCTCIDGA VGCTPLCLRV RPPRLWCPHP RRVSIPGHCC EQWVCEDDAK RPRKTAPRDT GAFDAVGEVE AWHRNCIAYT SPWSPCSTSC GLGVSTRISN VNAQCWPEQE SRLCNLRPCD VDIHTLIKAG KKCLAVYQPE ASMNFTLAGC ISTRSYQPKY CGVCMDNRCC IPYKSKTIDV SFQCPDGLGF SRQVLWINAC FCNLSCRNPN DIFADLESYP DFSEIAN -
Predicted molecular weight
39 kDa including tags -
Molecular weight information
The secreted recombinant human WISP1 consisting of 356 amino acids has a calculated molecular mass of 39 kDa. As a result of glycosylation, it migrates as an approximately 55 kDa protein in SDS-PAGE under reducing conditions. -
Amino acids
1 to 367 -
Tags
His tag C-Terminus -
Additional sequence information
Predicted N-terminus: Thr 23.
Specifications
Our Abpromise guarantee covers the use of ab276270 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- CCN 4
- CCN family member 4
- CCN4
see all -
Relevance
WISP1 is a downstream regulator in the Wnt/Frizzled-signaling pathway and is associated with cell survival. WISP1 attentuates p53-mediated apoptosis in response to DNA damage through activation of AKT kinase and up-regulates the anti-apoptotic Bcl-X(L) protein. WISP1 is expressed in heart, kidney, lung, pancreas, placenta, ovary, small intestine and spleen. Overexpression is associated with several cancers including breast cancer and colon tumors. -
Cellular localization
Secreted
Images
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SDS-PAGE - Recombinant Human WISP1 protein (ab276270)SDS-PAGE analysis of ab276270
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276270 has not yet been referenced specifically in any publications.
Preparation and Storage
- CCN 4
- CCN family member 4
- CCN4
Images
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SDS-PAGE - Recombinant Human WISP1 protein (ab276270)SDS-PAGE analysis of ab276270