Recombinant Human VEGFE protein (ab51001)
Key features and details
- Expression system: Baculovirus
- Purity: > 90% SDS-PAGE
- Suitable for: SDS-PAGE
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Product name
Recombinant Human VEGFE protein
See all VEGFE proteins and peptides -
Biological activity
ab51001 interacts with proteo-aminoglycans and heparan sulfate and with neuropillin 1. -
Purity
> 90 % SDS-PAGE.
> 90%, by SDS-PAGE and visualised by silver stain. Endotoxin level: -
Expression system
Baculovirus -
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
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Species
Human
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Preparation and Storage
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Relevance
Based on sequence similarity to VEGFA, a gene encoding a VEGF homologue has recently been discovered in the genome of Orf virus (OV) (Lyttle et al., 1994). Different isolates of Orf virus show significant amino acid sequence similarity to VEGFA and described as a viral virulence factor that appears to be derived from captured host genes. All eight cysteine residues of the central cysteine knot motif characteristic of members of the VEGF family are conserved among other residues in the VEGFE proteins (Dehio et al., 1999; Wise et al., 1999). Alignment of all mammalian VEGF sequences indicated that VEGFE is distinct from the previously described VEGFs but most closely related to VEGFA.
