Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human TRIM protein (ab173017)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

Description

  • Product name

    Recombinant Human TRIM protein

  • Purity

    > 95 % SDS-PAGE.
    ab173017 is greater than 95% pure, as determined by SEC-HPLC and reducing SDS-PAGE. It is supplied as an 0.2 µM filtered solution.

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    Q6PIZ9

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MNISHYVEKQRQDKMYSYSSDHTRVDEYYIEDTPIYGNLDDMISEPMDEN CYEQMKARPEKSVNKMQEATPSAQATNETQMCYASLDHSVKGKRRKPRKQ NTHFSDKDGDEQLHAIDASVSKTTLVDSFSPESQAVEENIHDDPIRLFGL IRAKREPIN

    • Predicted molecular weight

      19 kDa including tags

    • Amino acids

      29 to 186

    • Tags

      His tag C-Terminus

    • Specifications

    Our Abpromise guarantee covers the use of ab173017 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Liquid
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituents: 90% PBS, 10% Glycerol (glycerin, glycerine)

    General Info

    • Alternative names

      • HSPC062
      • pp29/30
      • T cell receptor interacting molecule
      • T-cell receptor-associated transmembrane adapter 1
      • T-cell receptor-interacting molecule
      • TCRIM
      • TRAT1
      • TRAT1_HUMAN
      • TRIM
      see all

    • Function

      Stabilizes the TCR (T-cell antigen receptor)/CD3 complex at the surface of T-cells.

    • Tissue specificity

      Strongly expressed in thymus, and to a lesser extent in spleen, lymph node and peripheral blood lymphocytes. Present in T-cells and NK cells, but not B-cells (at protein level).

    • Developmental stage

      Strongly expressed in fetal thymus at weeks 17-24 of gestation. Undetectable in bone marrow and fetal liver.

    • Post-translational
      modifications

      Phosphorylated on tyrosines by LCK or FYN upon TCR activation.

    • Cellular localization

      Cell membrane.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab173017? Please let us know so that we can cite the reference in this datasheet.

ab173017 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped on Dry Ice. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.40
    Constituents: 90% PBS, 10% Glycerol (glycerin, glycerine)

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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