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Signal Transduction Cytoskeleton / ECM Extracellular Matrix ECM Proteins Other ECM Proteins

Recombinant human Trefoil Factor 3 protein (ab269035)

Recombinant human Trefoil Factor 3 protein (ab269035)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: SDS-PAGE, Functional Studies

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Preparation and Storage

  • Alternative names

    • hITF
    • hP1.B
    • Intestinal trefoil factor
    • ITF
    • mITF
    • OTTMUSP00000021729
    • P1B
    • Polypeptide P1.B
    • TFF3
    • TFF3_HUMAN
    • TFI
    • TREFOIL
    • Trefoil factor (intestinal)
    • Trefoil factor 3
    see all
  • Function

    Involved in the maintenance and repair of the intestinal mucosa. Promotes the mobility of epithelial cells in healing processes (motogen).
  • Tissue specificity

    Expressed in goblet cells of the intestines and colon (at protein level). Expressed by goblet cells of small and large intestinal epithelia and also by the uterus.
  • Sequence similarities

    Contains 1 P-type (trefoil) domain.
  • Cellular localization

    Secreted > extracellular space > extracellular matrix > apical lamina.
  • Target information above from: UniProt accession Q07654 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • Functional Studies - Recombinant human Trefoil Factor 3 protein (ab269035)
    Functional Studies - Recombinant human Trefoil Factor 3 protein (ab269035)

    ab269035 stimulated MCF7 proliferation with an ED50 of 1-10 μg/mL.

  • SDS-PAGE - Recombinant human Trefoil Factor 3 protein (ab269035)
    SDS-PAGE - Recombinant human Trefoil Factor 3 protein (ab269035)

     SDS-PAGE analysis of ab269035.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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