Recombinant human TL1A protein (Active) (ab243769)
Key features and details
- Expression system: Escherichia coli
- Purity: > 97% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Suitable for: SDS-PAGE, Functional Studies, HPLC
Preparation and Storage
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Alternative names
- MGC129934
- MGC129935
- tl1
see all -
Function
Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis. -
Tissue specificity
Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon. -
Sequence similarities
Belongs to the tumor necrosis factor family. -
Cellular localization
Secreted and Membrane. - Information by UniProt