• Product name

  Recombinant human TL1A protein
  See all TL1A proteins and peptides

• Biological activity

  Determined by its ability to stimulate IFN-γ production by human PBMC using a concentration range of 10.0-100.0 ng/ml.
  Note: Results may vary with PBMC donors.

• Purity

  > 95 % SDS-PAGE.
  Greater than 98% by SDS-PAGE gel and HPLC analyses.
  

• Expression system

  Escherichia coli

• Protein length

  Protein fragment

• Animal free

  No

• Nature

  Recombinant

• • Species

    Human

  • Sequence

    QLRAQGEASV QFQALKGQEF APSHQQVYAP LRADGDKPRA HLTVVRQTPT QHFKNQFPAL HWEHELGLAF TKNRMNYTNK FLLIPESGDY FIYSQVTFRG MTSECSEIRQ AGRPNKPDSI TVVITKVTDS YPEPTQLLMG TKSVCEVGSN WFQPIYLGAM FSLQEGDKLM VNVSDISLVD YTKEDKTFFG AFLL

• Alternative names

  • MGC129934
  • MGC129935
  • tl1

  • TL1 A
  • tl1a
  • tnf ligand related molecule 1
  • TNF ligand-related molecule 1
  • tnf superfamily ligand tl1a
  • TNF15_HUMAN
  • TNFSF15
  • Tumor necrosis factor (ligand) superfamily member 15
  • Tumor necrosis factor ligand superfamily member 15
  • Tumor necrosis factor ligand superfamily member 15, secreted form
  • Vascular endothelial cell growth inhibitor
  • Vascular endothelial growth inhibitor
  • Vascular endothelial growth inhibitor 192a
  • vegi
  • VEGI192A

  see all

• Function

  Receptor for TNFRSF25 and TNFRSF6B. Mediates activation of NF-kappa-B. Inhibits vascular endothelial growth and angiogenesis (in vitro). Promotes activation of caspases and apoptosis.

• Tissue specificity

  Specifically expressed in endothelial cells. Detected in monocytes, placenta, lung, liver, kidney, skeletal muscle, pancreas, spleen, prostate, small intestine and colon.

• Sequence similarities

  Belongs to the tumor necrosis factor family.

• Cellular localization

  Secreted and Membrane.

• Target information above from: UniProt accession O95150 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt