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Recombinant human Tissue Plasminogen Activator protein (Active) (ab92637)

Key features and details

  • Expression system: CHO cells
  • Purity: > 95% SDS-PAGE
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant human Tissue Plasminogen Activator protein (Active)
    See all Tissue Plasminogen Activator proteins and peptides

  • Biological activity

    3,147,288 IU/mg (Relative to WHO International Standard for Human Recombinant Tissue Plasminogen Activator, NIBSC 98/714).

  • Purity

    > 95 % SDS-PAGE.
    Activated from single-chain form with immobilized plasmin. 100% complex formation with Human PAI1.

  • Expression system

    CHO cells

  • Accession

    P00750

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      SYQVICRDEK TQMIYQQHQS WLRPVLRSNR VEYCWCNSGR AQCHSVPVKS CSEPRCFNGG TCQQALYFSD FVCQCPEGFA GKCCEIDTRA TCYEDQGISY RGTWSTAESG AECTNWNSSA LAQKPYSGRR PDAIRLGLGN HNYCRNPDRD SKPWCYVFKA GKYSSEFCST PACSEGNSDC YFGNGSAYRG THSLTESGAS CLPWNSMILI GKVYTAQNPS AQALGLGKHN YCRNPDGDAK PWCHVLKNRR LTWEYCDVPS CSTCGLRQYS QPQFRIKGGL FADIASHPWQ AAIFAKHRRS PGERFLCGGI LISSCWILSA AHCFQERFPP HHLTVILGRT YRVVPGEEEQ KFEVEKYIVH KEFDDDTYDN DIALLQLKSD SSRCAQESSV VRTVCLPPAD LQLPDWTECE LSGYGKHEAL SPFYSERLKE AHVRLYPSSR CTSQHLLNRT VTDNMLCAGD TRSGGPQANL HDACQGDSGG PLVCLNDGRM TLVGIISWGL GCGQKDVPGV YTKVTNYLDW IRDNMRP

    • Predicted molecular weight

      59 kDa

    • Amino acids

      36 to 562

    • Additional sequence information

      Full length mature protein, without the propeptides and signal peptide.

Preparation and Storage

  • Stability and Storage

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.40
    Constituents: 9.52% HEPES, 0.58% Sodium chloride

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

Images

  • SDS-PAGE - Recombinant human Tissue Plasminogen Activator protein (Active) (ab92637)
    SDS-PAGE - Recombinant human Tissue Plasminogen Activator protein (Active) (ab92637)
    10% SDS-PAGE
    Lane 1: TPA Tissue Plasminogen Activator (3 ug) Non-reduced
    Lane 2: TPA Tissue Plasminogen Activator (3 ug) Reduced
    Lane 3: Prestained Standard

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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