Recombinant human TGF beta 3 protein (Active) (ab52313)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: HPLC, WB, Functional Studies, SDS-PAGE
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Product name
Recombinant human TGF beta 3 protein (Active)
See all TGF beta 3 proteins and peptides -
Biological activity
ab52313 is fully biologically active.
The ED50 was determined by cytotoxicity assay using the WHO standard 98/608 as a direct comparison is
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Purity
> 98 % SDS-PAGE.
>98% HPLC analyses -
Expression system
Escherichia coli -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS -
Predicted molecular weight
26 kDa -
Amino acids
301 to 412 -
Additional sequence information
(Gene symbol: TGFB3) (Gene ID: 7043)
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Preparation and Storage
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Alternative names
- ARVD
- ARVD1
- FLJ16571
see all -
Function
Involved in embryogenesis and cell differentiation. -
Involvement in disease
Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1) [MIM:107970]; also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall. -
Sequence similarities
Belongs to the TGF-beta family. -
Cellular localization
Secreted. - Information by UniProt
Images
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Functional Studies - Recombinant human TGF beta 3 protein (Active) (ab52313)
Cytotoxicity Assay of ab52313.
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Western blot - Recombinant human TGF beta 3 protein (ab52313)
