Recombinant Human PRAME protein (ab181886)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Suitable for: Sandwich ELISA, SDS-PAGE, WB
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Product name
Recombinant Human PRAME protein
See all PRAME proteins and peptides -
Purity
> 98 % SDS-PAGE. -
Expression system
Escherichia coli -
Accession
-
Protein length
Protein fragment -
Animal free
No -
Nature
Recombinant -
-
Species
Human -
Sequence
MNPLETLSITNCRLSEGDVMHLSQSPSVSQLSVLSLSGVMLTDVSPEPLQ ALLERASATLQDLVFDECGITDDQLLALLPSLSHCSQLTTLSFYGNSISI -
Predicted molecular weight
11 kDa -
Amino acids
321 to 420
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Preparation and Storage
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Alternative names
- 4930534P07Rik
- Cancer/testis antigen 130
- CT130
see all -
Function
Functions as a transcriptional repressor, inhibiting the signaling of retinoic acid through the retinoic acid receptors RARA, RARB and RARG. Prevents retinoic acid-induced cell proliferation arrest, differentiation and apoptosis. -
Tissue specificity
Expressed in testis. Detected in samples of kidney, brain and skin. -
Sequence similarities
Belongs to the PRAME family.
Contains 4 LRR (leucine-rich) repeats. -
Cellular localization
Nucleus. Cell membrane. - Information by UniProt
Images
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Sandwich ELISA - Recombinant Human PRAME protein (ab181886)
Sandwich ELISA using ab181886 as standard.
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SDS-PAGE - Recombinant Human PRAME protein (ab181886)15% SDS PAGE analysis of ab181886 under reducing conditions, stained with Coomassie blue.
