Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human PF4 protein (ab9562)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant human PF4 protein
    See all PF4 proteins and peptides

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Accession

    P02776

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      EAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES

    • Predicted molecular weight

      8 kDa

    • Amino acids

      31 to 101

    • Associated products

    Specifications

    Our Abpromise guarantee covers the use of ab9562 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      SDS-PAGE

    • Form

      Lyophilized

    • Additional notes

      The biological activity of this product is determined by its ability to chemoattract human fibroblasts using a concentration range of 1.0-10.0 ng/ml.
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      Reconstitute in 200ul sterile water to a conc. of 0.1 mg/ml.

    General Info

    • Alternative names

      • C-X-C motif chemokine 4
      • Chemokine (C X C motif) ligand 4
      • Chemokine (CXC motif) ligand 4
      • chemokine ligand 4
      • CXCL 4
      • CXCL4
      • Iroplact
      • MGC138298
      • Oncostatin A
      • Oncostatin-A
      • OncostatinA
      • PF 4
      • PF-4
      • PF4
      • Pf4a
      • Platelet factor 4
      • PLF4_HUMAN
      • SCYB 4
      • SCYB4
      • short form
      • Small inducible cytokine subfamily B
      • Small inducible cytokine subfamily member 4
      see all

    • Function

      Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.

    • Sequence similarities

      Belongs to the intercrine alpha (chemokine CxC) family.

    • Post-translational
      modifications

      Binds non-covalently to a proteoglycan molecule.

    • Cellular localization

      Secreted.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab9562? Please let us know so that we can cite the reference in this datasheet.

ab9562 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    Reconstitute in 200ul sterile water to a conc. of 0.1 mg/ml.

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
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