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Cardiovascular Atherosclerosis Thrombosis Platelets

Recombinant human PDGF AA protein (Animal Free) (ab179505)

Recombinant human PDGF AA protein (Animal Free) (ab179505)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 97% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

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Preparation and Storage

  • Alternative names

    • PDGF A
    • PDGF A chain
    • PDGF subunit A
    • PDGF-1
    • PDGF1
    • PDGFA
    • PDGFA_HUMAN
    • Platelet derived growth factor alpha chain
    • Platelet derived growth factor alpha isoform 2 preproprotein
    • Platelet derived growth factor alpha polypeptide
    • Platelet-derived growth factor A chain
    • Platelet-derived growth factor alpha polypeptide
    • Platelet-derived growth factor subunit A
    see all
  • Function

    Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.
  • Sequence similarities

    Belongs to the PDGF/VEGF growth factor family.
  • Domain

    The long form contains a basic insert which acts as a cell retention signal.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P04085 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • SDS-PAGE - Recombinant human PDGF AA protein (Animal Free) (ab179505)
    SDS-PAGE - Recombinant human PDGF AA protein (Animal Free) (ab179505)

     SDS PAGE analysis of ab179505 under non-reducing (-) and reducing (+) conditions. Stained with Coomassie Blue.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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