Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human PDGF AA protein (ab9702)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant human PDGF AA protein
    See all PDGF AA proteins and peptides

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Predicted molecular weight

      24 kDa

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab9702 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        Functional Studies

        SDS-PAGE

      • Form

        Lyophilized

      • Additional notes

        The biological activity is determined by the dose-dependent stimulation of the proliferation of BALB/c 3T3 cells, is 1 x 106 units/mg
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

        Constituent: 0.06% Acetic acid

        This product is an active protein and may elicit a biological response in vivo, handle with caution.

      • Reconstitution
        For lot specific reconstitution information please contact our Scientific Support Team.

      General Info

      • Alternative names

        • PDGF A
        • PDGF A chain
        • PDGF subunit A
        • PDGF-1
        • PDGF1
        • PDGFA
        • PDGFA_HUMAN
        • Platelet derived growth factor alpha chain
        • Platelet derived growth factor alpha isoform 2 preproprotein
        • Platelet derived growth factor alpha polypeptide
        • Platelet-derived growth factor A chain
        • Platelet-derived growth factor alpha polypeptide
        • Platelet-derived growth factor subunit A
        see all

      • Function

        Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

      • Sequence similarities

        Belongs to the PDGF/VEGF growth factor family.

      • Domain

        The long form contains a basic insert which acts as a cell retention signal.

      • Cellular localization

        Secreted.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (1)

    Publishing research using ab9702? Please let us know so that we can cite the reference in this datasheet.

    ab9702 has been referenced in 1 publication.

    • Gomez JA  et al. Ventral tegmental area astrocytes orchestrate avoidance and approach behavior. Nat Commun 10:1455 (2019). PubMed: 30926783

    Preparation and Storage

    • Alternative names

      • PDGF A
      • PDGF A chain
      • PDGF subunit A
      • PDGF-1
      • PDGF1
      • PDGFA
      • PDGFA_HUMAN
      • Platelet derived growth factor alpha chain
      • Platelet derived growth factor alpha isoform 2 preproprotein
      • Platelet derived growth factor alpha polypeptide
      • Platelet-derived growth factor A chain
      • Platelet-derived growth factor alpha polypeptide
      • Platelet-derived growth factor subunit A
      see all

    • Function

      Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.

    • Sequence similarities

      Belongs to the PDGF/VEGF growth factor family.

    • Domain

      The long form contains a basic insert which acts as a cell retention signal.

    • Cellular localization

      Secreted.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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