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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Recombinant human Oncostatin M/OSM protein (ab167707)

Recombinant human Oncostatin M/OSM protein (ab167707)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

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Preparation and Storage

  • Alternative names

    • MGC20461
    • ONCM_HUMAN
    • Oncostatin M
    • Oncostatin-M
    • OSM
    see all
  • Function

    Growth regulator. Inhibits the proliferation of a number of tumor cell lines. Stimulates proliferation of AIDS-KS cells. It regulates cytokine production, including IL-6, G-CSF and GM-CSF from endothelial cells. Uses both type I OSM receptor (heterodimers composed of LIPR and IL6ST) and type II OSM receptor (heterodimers composed of OSMR and IL6ST).
  • Sequence similarities

    Belongs to the LIF/OSM family.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P13725 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • Functional Studies - Recombinant human Oncostatin M/OSM protein (ab167707)
    Functional Studies - Recombinant human Oncostatin M/OSM protein (ab167707)
    Immobilized Human OSM, Tag Free at 5 µg/mL (100 µL/well) can bind Human LIF R, Fc Tag with a linear range of 0.01-0.156 µg/mL.
  • SDS-PAGE - Recombinant human Oncostatin M/OSM protein (ab167707)
    SDS-PAGE - Recombinant human Oncostatin M/OSM protein (ab167707)
    SDS-PAGE of reduced ab167707 stained overnight with Coomassie Blue.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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