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Neuroscience Cell Type Marker Glia marker Oligodendrocyte marker

Recombinant Human Oligodendrocyte Specific Protein (Fc Chimera) (ab276494)

Recombinant Human Oligodendrocyte Specific Protein (Fc Chimera) (ab276494)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 90% SDS-PAGE
  • Endotoxin level:
  • Tags: Fc tag N-Terminus
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human Oligodendrocyte Specific Protein (Fc Chimera)
    See all Oligodendrocyte Specific Protein proteins and peptides
  • Purity

    > 90 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells
  • Accession

    O75508
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      VTTSTNDWVV TCGYTIPTCR KLDELGSKGL WADCVMATGL YHCKPLVDIL ILPGYVQACR
    • Predicted molecular weight

      33 kDa including tags
    • Molecular weight information

      The recombinant human CLDN11/mFc comprises 296 amino acids and has a predicted molecular mass of 33.2 kDa. The apparent molecular mass of the monomer is approximately 37 kDa in SDS-PAGE under reducing conditions due to glycosylation.
    • Amino acids

      23 to 82
    • Tags

      Fc tag N-Terminus
    • Additional sequence information

      Fc region of muse IgG1. Predicted N-terminus: Asp.
  • Specifications

    Our Abpromise guarantee covers the use of ab276494 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.40
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • Claudin 11
      • Claudin-11
      • CLD11_HUMAN
      • Cldn11
      • Oligodendrocyte transmembrane protein
      • Oligodendrocyte-specific protein
      • OSP
      • OTM
      see all
    • Function

      Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.
    • Sequence similarities

      Belongs to the claudin family.
    • Cellular localization

      Cell junction > tight junction. Cell membrane.
    • Target information above from: UniProt accession O75508 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Oligodendrocyte Specific Protein (ab276494)
    SDS-PAGE - Recombinant Human Oligodendrocyte Specific Protein (ab276494)
    SDS-PAGE analysis of ab276494

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab276494? Please let us know so that we can cite the reference in this datasheet.

    ab276494 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Claudin 11
    • Claudin-11
    • CLD11_HUMAN

    Images

    • SDS-PAGE - Recombinant Human Oligodendrocyte Specific Protein (ab276494)
      SDS-PAGE - Recombinant Human Oligodendrocyte Specific Protein (ab276494)
      SDS-PAGE analysis of ab276494

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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