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Signal Transduction Growth Factors/Hormones TGF

Recombinant Human Myostatin Propeptide protein (ab63300)

Recombinant Human Myostatin Propeptide protein (ab63300)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Suitable for: WB, ELISA

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Description

  • Product name

    Recombinant Human Myostatin Propeptide protein
    See all Myostatin Propeptide proteins and peptides
  • Purity

    > 95 % SDS-PAGE.

  • Expression system

    Escherichia coli
  • Accession

    O14793
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      MGNENSEQKE NVEKEGLCNA CTWRQNTKSS RIEAIKIQIL SKLRLETAPN ISKDVIRQLL PKAPPLRELI DQYDVQRDDS SDGSLEDDDY HATTETIITM PTESDFLMQV DGKPKCCFFK FSSKIQYNKV VKAQLWIYLR PVETPTTVFV QILRLIKPMK DGTRYTGIRS LKLDMNPGTG IWQSIDVKTV LQNWLKQPES NLGIEIKALD ENGHDLAVTF PGPGEDGLNP FLEVKVTDTP KRSRRKLN
    • Amino acids

      24 to 266

Preparation and Storage

  • Alternative names

    • Cmpt
    • GDF-8
    • GDF8_HUMAN
    • Growth/differentiation factor 8
    • MSLHP
    • MSTN
    • MSTN myostatin
    • Myostatin
    • Myostatin Propeptide
    see all
  • Function

    Acts specifically as a negative regulator of skeletal muscle growth.
  • Involvement in disease

    Defects in MSTN are the cause of muscle hypertrophy (MSLHP) [MIM:614160]. MSLHP is a condition characterized by increased muscle bulk and strength. Affected individuals are exceptionally strong.
  • Sequence similarities

    Belongs to the TGF-beta family.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession O14793 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt

Images

  • SDS-PAGE - Recombinant Human Myostatin Propeptide protein (ab63300)
    SDS-PAGE - Recombinant Human Myostatin Propeptide protein (ab63300)
    LANES:
    1. MW marker – 14, 21, 31, 45, 66, 97 kDa 2. reduced and heated sample, 7μg/lane
    3. non-reduced and non-heated sample, 7μg/lane

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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