Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human IgG3 protein (ab276600)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 96% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Human IgG3 protein
    See all IgG3 proteins and peptides

  • Purity

    > 96 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    P01860

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      ELKTPLGDTT HTCPRCPEPK SCDTPPPCPR CPEPKSCDTP PPCPRCPEPK SCDTPPPCPR CPAPELLGGP SVFLFPPKPK DTLMISRTPE VTCVVVDVSH EDPEVQFKWY VDGVEVHNAK TKPREEQYNS TFRVVSVLTV LHQDWLNGKE YKCKVSNKAL PAPIEKTISK TKGQPREPQV YTLPPSREEM TKNQVSLTCL VKGFYPSDIA VEWESSGQPE NNYNTTPPML DSDGSFFLYS KLTVDKSRWQ QGNIFSCSVM HEALHNRFTQ KSLSLSPGK

    • Predicted molecular weight

      31 kDa including tags

    • Molecular weight information

      The recombinant human IgG3-Fc consists of 279 amino acids and has a predicted molecular mass of 31.2 kDa. As a result of glycosylation, the apparent molecular mass of IgG3-Fc is approximately 38 kDa in SDS-PAGE under reducing conditions.

    • Amino acids

      99 to 377

    • Additional sequence information

      Predicted N-terminus: Glu 99.

    • Specifications

    Our Abpromise guarantee covers the use of ab276600 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.4
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • DKFZp686H11213
      • FLJ39988
      • FLJ40036
      • FLJ40253
      • FLJ40587
      • FLJ40789
      • FLJ40834
      • HDC
      • Heavy chain disease protein
      • Ig gamma 3 chain C region
      • IGHG3
      • Immunoglobulin heavy constant gamma 3 (G3m marker)
      • MGC45809
      see all

    • Relevance

      IgG3, like IgG1, activates complement and has an affinity for fc receptors; thus IgG1 and IgG3 are the more effective of the IgG subclasses. An IgG3 deficiency is associated with Wiscott-Aldrich disease, systemic lupus erythematosus, juvenile diabetes mellitus, and peridontal infections. IgG anti-viral antibodies are restricted to IgG subclasses 1 and 3, with IgG3 antibodies being the first to appear in response to infection.

    • Cellular localization

      Secreted

Images

  • SDS-PAGE - Recombinant Human IgG3 protein (ab276600)
    SDS-PAGE - Recombinant Human IgG3 protein (ab276600)
    SDS-PAGE analysis of ab276600

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab276600? Please let us know so that we can cite the reference in this datasheet.

ab276600 has not yet been referenced specifically in any publications.

Preparation and Storage

  • DKFZp686H11213
  • FLJ39988
  • FLJ40036

Images

  • SDS-PAGE - Recombinant Human IgG3 protein (ab276600)
    SDS-PAGE - Recombinant Human IgG3 protein (ab276600)
    SDS-PAGE analysis of ab276600

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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