Recombinant Human ICAM2 protein (Fc Chimera His Tag) (ab276250)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 97% SDS-PAGE
- Endotoxin level:
- Tags: His tag C-Terminus, Fc tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human ICAM2 protein (Fc Chimera His Tag)
See all ICAM2 proteins and peptides -
Purity
> 97 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Protein fragmentAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
MSSFGYRTLT VALFTLICCP GSDEKVFEVH VRPKKLAVEP KGSLEVNCST TCNQPEVGGL ETSLDKILLD EQAQWKHYLV SNISHDTVLQ CHFTCSGKQE SMNSNVSVYQ PPRQVILTLQ PTLVAVGKSF TIECRVPTVE PLDSLTLFLF RGNETLHYET FGKAAPAPQE ATATFNSTAD REDGHRNFSC LAVLDLMSRG GNIFHKHSAP KMLEIYEPVS DSQ -
Predicted molecular weight
50 kDa including tags -
Molecular weight information
The recombinant human ICAM2/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 449 amino acids and has a predicted molecular mass of 50.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhICAM2/Fc monomer is approximately 85-95 kDa due to glycosylation. -
Amino acids
1 to 223 -
Tags
His tag C-Terminus , Fc tag C-Terminus -
Additional sequence information
Human IgG1 Fc tag at C-terminus. Predicted N-terminus: Ser 22.
Specifications
Our Abpromise guarantee covers the use of ab276250 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- CD102
- CD102 antigen
- ICAM 2
see all -
Relevance
ICAM2 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin like C2 type domains, and bind to the leukocyte adhesion LFA1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA1 dependent cell adhesion. It mediates adhesive interactions important for antigen specific immune response, NK cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. -
Cellular localization
Membrane; Single-pass type I membrane protein
Images
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SDS-PAGE - Recombinant Human ICAM2 protein (ab276250)SDS-PAGE analysis of ab276250
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276250 has not yet been referenced specifically in any publications.
Preparation and Storage
- CD102
- CD102 antigen
- ICAM 2
Images
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SDS-PAGE - Recombinant Human ICAM2 protein (ab276250)SDS-PAGE analysis of ab276250