Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human HSD17B14 protein (His tag) (ab276634)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Human HSD17B14 protein (His tag)
    See all HSD17B14 proteins and peptides

  • Purity

    > 95 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    HEK 293 cells

  • Accession

    Q9BPX1

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      MATGTRYAGK VVVVTGGGRG IGAGIVRAFV NSGARVVICD KDESGGRALE QELPGAVFIL CDVTQEDDVK TLVSETIRRF GRLDCVVNNA GHHPPPQRPE ETSAQGFRQL LELNLLGTYT LTKLALPYLR KSQGNVINIS SLVGAIGQAQ AVPYVATKGA VTAMTKALAL DESPYGVRVN CISPGNIWTP LWEELAALMP DPRATIREGM LAQPLGRMGQ PAEVGAAAVF LASEANFCTG IELLVTGGAE LGYGCKASRS TPVDAPDIPS

    • Predicted molecular weight

      30 kDa including tags

    • Molecular weight information

      The recombinant human HSD17B14 consists 281 amino acids and predicts a molecular mass of 29.8 kDa.

    • Amino acids

      1 to 270

    • Tags

      His tag C-Terminus

    • Additional sequence information

      Predicted N-terminus: Met.

    • Specifications

    Our Abpromise guarantee covers the use of ab276634 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      pH: 7.4
      Constituent: 100% PBS

    • Reconstitution
      This information is lot specific. Please contact our technical Support team for details.

    General Info

    • Alternative names

      • 17 beta HSD 14
      • 17 beta hydroxysteroid dehydrogenase 14
      • 17 beta hydroxysteroid dehydrogenase DHRS10
      • Dehydrogenase/reductase (SDR family) member 10
      • Dehydrogenase/reductase SDR family member 10
      • DHRS10
      • Hydroxysteroid (17 beta) dehydrogenase 14
      • Retinal short chain dehydrogenase/reductase 3
      • Retinal short chain dehydrogenase/reductase retSDR3
      • retSDR3
      • SDR3
      • SDR47C1
      • Short chain dehydrogenase/reductase family 47C, member 1
      see all

    • Relevance

      HSD17B14 belongs to the short-chain dehydrogenases/reductases (SDR) family. It has NAD-dependent 17-beta-hydroxysteroid dehydrogenase activity and converts oestradiol to oestrone. The physiological substrate is not known. HSD17B14 acts on oestradiol and 5-androstene-3-beta,17-beta-diol (in vitro). It is highly expressed in brain, placenta, liver and kidney.

    • Cellular localization

      Cytoplasmic

Images

  • SDS-PAGE - Recombinant Human HSD17B14 protein (ab276634)
    SDS-PAGE - Recombinant Human HSD17B14 protein (ab276634)
    SDS-PAGE analysis of ab276634

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab276634? Please let us know so that we can cite the reference in this datasheet.

ab276634 has not yet been referenced specifically in any publications.

Preparation and Storage

  • 17 beta HSD 14
  • 17 beta hydroxysteroid dehydrogenase 14
  • 17 beta hydroxysteroid dehydrogenase DHRS10

Images

  • SDS-PAGE - Recombinant Human HSD17B14 protein (ab276634)
    SDS-PAGE - Recombinant Human HSD17B14 protein (ab276634)
    SDS-PAGE analysis of ab276634

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