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Neuroscience Neurology process Neurogenesis

Recombinant Human GMFB protein (ab54143)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

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Description

  • Product name

    Recombinant Human GMFB protein
    See all GMFB proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    Purity : Greater than 98% by SDS-PAGE gel and HPLC analyses.
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      SESLVVCDVA EDLVEKLRKF RFRKETNNAA IIMKIDKDKR LVVLDEELEG ISPDELKDEL PERQPRFIVY SYKYQHDDGR VSYPLCFIFS SPVGCKPEQQ MMYAGSKNKL VQTAELTKVF EIRNTEDLTE EWLREKLGFF H
  • Specifications

    Our Abpromise guarantee covers the use of ab54143 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

    • Form

      Lyophilized
    • Additional notes

      This product was previously labelled as GMF beta

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Upon delivery aliquot. Upon reconsitution add a carrier protein (0.1% BSA). Store at -20°C. Aliquot the reconstituted solution and re-lyophilize. The re-lyophilized aliquoted peptide should be stored dry at 4°C, preferably in a desiccator. For long term storage it is recommended to add a carrier protein on reconstitution (0.1% HSA or BSA). Working aliquots stored with a carrier protein are stable for at least 3 months at -20°C to -80°C..

    • Reconstitution
      For lot specific reconstitution information please contact our Scientific Support Team.

    General Info

    • Alternative names

      • Glia maturation factor beta
      • GMF
      • GMF-beta
      • GMFB
      • GMFB_HUMAN
      see all
    • Function

      This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
    • Sequence similarities

      Belongs to the actin-binding proteins ADF family. GMF subfamily.
      Contains 1 ADF-H domain.
    • Post-translational
      modifications

      Phosphorylated; stimulated by phorbol ester.
    • Target information above from: UniProt accession P60983 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (1)

    Publishing research using ab54143? Please let us know so that we can cite the reference in this datasheet.

    ab54143 has been referenced in 1 publication.

    • Qureshi OS  et al. Multivalent Fc?-receptor engagement by a hexameric Fc-fusion protein triggers Fc?-receptor internalisation and modulation of Fc?-receptor functions. Sci Rep 7:17049 (2017). PubMed: 29213127

    Preparation and Storage

    • Glia maturation factor beta
    • GMF
    • GMF-beta

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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