Recombinant Human DPP2 protein (His tag) (ab276311)
Key features and details
- Expression system: HEK 293 cells
- Purity: > 98% SDS-PAGE
- Endotoxin level:
- Tags: His tag C-Terminus
- Suitable for: SDS-PAGE
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Product name
Recombinant Human DPP2 protein (His tag)
See all DPP2 proteins and peptides -
Purity
> 98 % SDS-PAGE. -
Endotoxin level
Expression system
HEK 293 cellsAccession
Protein length
Full length proteinAnimal free
NoNature
Recombinant-
Species
Human -
Sequence
MGSAPWAPVL LLALGLRGLQ AGARRAPDPG FQERFFQQRL DHFNFERFGN KTFPQRFLVS DRFWVRGEGP IFFYTGNEGD VWAFANNSAF VAELAAERGA LLVFAEHRYY GKSLPFGAQS TQRGHTELLT VEQALADFAE LLRALRRDLG AQDAPAIAFG GSYGGMLSAY LRMKYPHLVA GALAASAPVL AVAGLGDSNQ FFRDVTADFE GQSPKCTQGV REAFRQIKDL FLQGAYDTVR WEFGTCQPLS DEKDLTQLFM FARNAFTVLA MMDYPYPTDF LGPLPANPVK VGCDRLLSEA QRITGLRALA GLVYNASGSE HCYDIYRLYH SCADPTGCGT GPDARAWDYQ ACTEINLTFA SNNVTDMFPD LPFTDELRQR YCLDTWGVWP RPDWLLTSFW GGDLRAASNI IFSNGNLDPW AGGGIRRNLS ASVIAVTIQG GAHHLDLRAS HPEDPASVVE ARKLEATIIG EWVKAARREQ QPALRGGPRL SL -
Predicted molecular weight
54 kDa including tags -
Molecular weight information
The secreted recombinant human DPPII comprises 482 amino acids with a predicted molecular mass of 53.6 kDa. As a result of glycosylation, rh DPPII migrates as an approximately 60 kDa band in SDS-PAGE under reducing conditions. -
Amino acids
1 to 492 -
Tags
His tag C-Terminus -
Additional sequence information
Predicted N-terminus: Gly 22.
Specifications
Our Abpromise guarantee covers the use of ab276311 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
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Applications
SDS-PAGE
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Form
Lyophilized -
Concentration information loading...
Preparation and Storage
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Stability and Storage
Shipped at Room Temperature. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 7.40
Constituent: 100% PBS -
ReconstitutionThis information is lot specific. Please contact our technical Support team for details.
General Info
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Alternative names
- Dipeptidyl aminopeptidase II
- Dipeptidyl peptidase 7
- Dipeptidyl peptidase II
see all -
Relevance
DPP2 is a serine protease found most abundantly in the lysosome. There is also a non-lysosomal membrane-associated form of DPP2 reported in the rat brain (DPP-II-M), and a soluble form (DPP-II-S). First discovered as an enzyme involved in the terminal steps of protein degradation, and later as an enzyme involved in cell growth and quiescence, DPP2 cleaves N-terminal dipeptides and tripeptides from proteins. DPP2 has a preference for proline in the P1 position, and processes the tripeptides generated by DPP1 (which is unable to cleave if proline is in the P1 position). Some tumor cell lines express elevated DPP2 levels, and serum levels of DPP2 are elevated in some cancer patients, making DPP2 a potential tumor marker. DPP2 levels have been also been reported to be elevated in the cerebral spinal fluid from Parkinson’s patients. -
Cellular localization
Lysosome. Cytoplasmic vesicle. Secreted.
Images
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SDS-PAGE - Recombinant Human DPP2 protein (ab276311)SDS-PAGE analysis of ab276311
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab276311 has not yet been referenced specifically in any publications.
Preparation and Storage
- Dipeptidyl aminopeptidase II
- Dipeptidyl peptidase 7
- Dipeptidyl peptidase II
Images
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SDS-PAGE - Recombinant Human DPP2 protein (ab276311)SDS-PAGE analysis of ab276311