Anti-p92 antibody (ab72210)
Key features and details
- Rabbit polyclonal to p92
- Suitable for: WB
- Reacts with: Mouse
- Isotype: IgG
Overview
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Product name
Anti-p92 antibody -
Description
Rabbit polyclonal to p92 -
Host species
Rabbit -
Tested Applications & Species
See all applications and species dataApplication Species WB Mouse -
Immunogen
Synthetic peptide corresponding to Mouse p92 aa 750 to the C-terminus conjugated to keyhole limpet haemocyanin.
(Peptide available asab87446) -
General notes
This product may be covered by one or more of the following U.S. Patents.
6,166,192
6,426,411
6,525,178
6,872,391
6,908,987
7,250,283
7,091,006
7,354,738
8,105,774
8,445,233Previously labelled as Advillin.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.40
Preservative: 0.02% Sodium azide
Constituent: PBS
Batches of this product that have a concentrationConcentration information loading...Purity
Immunogen affinity purifiedClonality
PolyclonalIsotype
IgGResearch areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab72210 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
GuaranteedTested applications are guaranteed to work and covered by our Abpromise guarantee.
PredictedPredicted to work for this combination of applications and species but not guaranteed.
IncompatibleDoes not work for this combination of applications and species.
Application Species WB MouseAll applications RatHumanApplication Abreviews Notes WB Use a concentration of 1 µg/ml. Detects a band of approximately 92 kDa (predicted molecular weight: 92 kDa).Notes WB
Use a concentration of 1 µg/ml. Detects a band of approximately 92 kDa (predicted molecular weight: 92 kDa).Target
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Function
Ca(2+)-regulated actin-binding protein. May have a unique function in the morphogenesis of neuronal cells which form ganglia. Required for SREC1-mediated regulation of neurite-like outgrowth. Plays a role in regenerative sensory axon outgrowth and remodeling processes after peripheral injury in neonates. Involved in the formation of long fine actin-containing filopodia-like structures in fibroblast. Plays a role in ciliogenesis. -
Tissue specificity
Most highly expressed in the small intestine and colonic lining. Weaker expression also detected in the thymus, prostate, testes and uterus. -
Sequence similarities
Belongs to the villin/gelsolin family.
Contains 6 gelsolin-like repeats.
Contains 1 HP (headpiece) domain. -
Cellular localization
Cytoplasm > cytoskeleton. Cell projection. Cell projection > axon. - Information by UniProt
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Database links
- Entrez Gene: 10677 Human
- Entrez Gene: 11567 Mouse
- Entrez Gene: 79253 Rat
- Omim: 613397 Human
- SwissProt: O75366 Human
- SwissProt: O88398 Mouse
- SwissProt: Q9WU06 Rat
- Unigene: 584854 Human
see all -
Alternative names
- Actin binding protein DOC 6 antibody
- Actin binding protein DOC6 antibody
- Advil antibody
see all
Images
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All lanes : Anti-p92 antibody (ab72210) at 1 µg/ml
Lane 1 : Brain (Mouse) Tissue Lysate
Lane 2 :Mouse skin tissue lysate - total protein (ab4025)
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 92 kDa
Observed band size: 92 kDa
Additional bands at: 105 kDa, 52 kDa. We are unsure as to the identity of these extra bands.
Protocols
Datasheets and documents
References (3)
ab72210 has been referenced in 3 publications.
- Esmaeilniakooshkghazi A et al. Mouse intestinal tuft cells express advillin but not villin. Sci Rep 10:8877 (2020). PubMed: 32483224
- Xie Z et al. A cytoskeleton regulator AVIL drives tumorigenesis in glioblastoma. Nat Commun 11:3457 (2020). PubMed: 32651364
- Nonomura K et al. Piezo2 senses airway stretch and mediates lung inflation-induced apnoea. Nature 541:176-181 (2017). PubMed: 28002412
Images
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All lanes : Anti-p92 antibody (ab72210) at 1 µg/ml
Lane 1 : Brain (Mouse) Tissue Lysate
Lane 2 :Mouse skin tissue lysate - total protein (ab4025)
Lysates/proteins at 10 µg per lane.
Secondary
All lanes : Goat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilution
Developed using the ECL technique.
Performed under reducing conditions.
Predicted band size: 92 kDa
Observed band size: 92 kDa
Additional bands at: 105 kDa, 52 kDa. We are unsure as to the identity of these extra bands.