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Recombinant Human DcR1 protein (ab151632)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

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Description

  • Product name

    Recombinant Human DcR1 protein
  • Purity

    > 95 % SDS-PAGE.
    ab151632 is greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE.
  • Endotoxin level

  • Expression system

    HEK 293 cells
  • Accession

    O14798
  • Protein length

    Protein fragment
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      ATTARQEEVPQQTVAPQQQRHSFKGEECPAGSHRSEHTGACNPCTEGVDY TNASNNEPSC FPCTVCKSDQKHKSSCTMTRDTVCQCKEGTFRNENSPEMCRKCSRCPSGE VQVSNCTSWD DIQCVEEFGANATVETPAAEETMNTSPGTPAPAAEETMNTSPGTPAPAAE ETMTTSPGTP APAAEETMTTSPGTPAVDHHHHHH
    • Predicted molecular weight

      22 kDa including tags
    • Amino acids

      26 to 221
    • Tags

      His tag C-Terminus
  • Associated products

    • Related Products

      • Anti-DcR1 antibody (ab1674)
      • Anti-6X His tag® antibody [HIS.H8] (ab18184)
      • Anti-DcR1 antibody (ab2087)
      • Anti-6X His tag® antibody [4D11] (ab5000)
      • Anti-6X His tag® antibody (ab9108)

    Specifications

    Our Abpromise guarantee covers the use of ab151632 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      SDS-PAGE

      HPLC

    • Form

      Lyophilized
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

      pH: 7.2
      Constituents: 64% Sodium chloride, 3% Sodium phosphate monobasic, monohydrate, 28% disodium;hydrogen phosphate;dodecahydrate

    • Reconstitution
      Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    General Info

    • Alternative names

      • Antagonist decoy receptor for TRAIL/Apo 2L
      • CD263
      • Cytotoxic TRAIL receptor 3
      • DCR1
      • DCR1 TNFR
      • Decoy Receptor 1
      • Decoy TRAIL receptor without death domain
      • LIT
      • Lymphocyte inhibitor of TRAIL
      • MGC149501
      • MGC149502
      • TNF related apoptosis inducing ligand receptor 3
      • TNF-re ated apoptosis inducing ligand receptor 3
      • TNFRSF10C
      • TRAIL R3
      • TRAIL receptor 3
      • TRAILR3
      • TRID
      • Tumor necrosis factor receptor superfamily member 10C
      • Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain
      see all
    • Relevance

      DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis.
    • Cellular localization

      Cell Membrane and Cytoplasmic

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab151632? Please let us know so that we can cite the reference in this datasheet.

    ab151632 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. After reconstitution store at -20ºC. Avoid freeze / thaw cycles.

      pH: 7.2
      Constituents: 64% Sodium chloride, 3% Sodium phosphate monobasic, monohydrate, 28% disodium;hydrogen phosphate;dodecahydrate

    • Reconstitution
      Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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