Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human CXCL11 protein (ab9956)

Key features and details

  • Expression system: Escherichia coli
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant human CXCL11 protein
    See all CXCL11 proteins and peptides

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Protein length

    Full length protein

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Predicted molecular weight

      10 kDa

    • Associated products

    Specifications

    Our Abpromise guarantee covers the use of ab9956 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      SDS-PAGE

    • Form

      Lyophilized

    • Additional notes

      The biological activity of this product is determined by a chemotaxis assay using IL-2 activated human T cells. Significant chemotaxis was achieved at a concentration range of 0.1-10.0 ng/ml.
    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      For lot specific reconstitution information please contact our Scientific Support Team.

    General Info

    • Alternative names

      • b R1
      • b-R1
      • Beta-R1
      • betaR1
      • C-X-C motif chemokine 11
      • Chemokine (C-X-C motif) ligand 11
      • Chemokine C-X-C motif ligand 11
      • CXC11
      • CXCL11
      • CXL11_HUMAN
      • H174
      • I TAC
      • I-TAC
      • Interferon gamma inducible protein 9
      • Interferon gamma-inducible protein 9
      • Interferon inducible T cell alpha chemoattractant
      • Interferon-inducible T-cell a chemoattractant I-TAC
      • Interferon-inducible T-cell alpha chemoattractant
      • IP 9
      • IP-9
      • IP9
      • ITAC
      • MGC102770
      • SCYB11
      • SCYB9B
      • Small inducible cytokine B11
      • Small inducible cytokine subfamily B (Cys-X-Cys) member 11
      • Small inducible cytokine subfamily B (Cys-X-Cys) member 9B
      • Small inducible cytokine subfamily B, member 11
      • Small inducible cytokine subfamily B, member 9B
      • Small-inducible cytokine B11
      see all

    • Function

      Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.

    • Tissue specificity

      High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.

    • Sequence similarities

      Belongs to the intercrine alpha (chemokine CxC) family.

    • Cellular localization

      Secreted.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab9956? Please let us know so that we can cite the reference in this datasheet.

ab9956 has not yet been referenced specifically in any publications.

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • Reconstitution
    For lot specific reconstitution information please contact our Scientific Support Team.

Images

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

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