Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Expression system: Escherichia coli
Endotoxin level:
Active: Yes
Suitable for: Functional Studies, SDS-PAGE

Product name

Recombinant human CXCL11 protein
See all CXCL11 proteins and peptides
Endotoxin level
Expression system

Escherichia coli
Protein length

Full length protein
Animal free

No
Nature

Recombinant
- Species
  
  Human
- Predicted molecular weight
  
  10 kDa

Related Products
- Anti-CXCL11 antibody (ab9955)

Our Abpromise guarantee covers the use of ab9956 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Applications

Functional Studies

SDS-PAGE
Form

Lyophilized
Additional notes

The biological activity of this product is determined by a chemotaxis assay using IL-2 activated human T cells. Significant chemotaxis was achieved at a concentration range of 0.1-10.0 ng/ml.
Concentration information loading...

Stability and Storage

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

This product is an active protein and may elicit a biological response in vivo, handle with caution.
Reconstitution

For lot specific reconstitution information please contact our Scientific Support Team.

Alternative names
- b R1
- b-R1
- Beta-R1
- betaR1
- C-X-C motif chemokine 11
- Chemokine (C-X-C motif) ligand 11
- Chemokine C-X-C motif ligand 11
- CXC11
- CXCL11
- CXL11_HUMAN
- H174
- I TAC
- I-TAC
- Interferon gamma inducible protein 9
- Interferon gamma-inducible protein 9
- Interferon inducible T cell alpha chemoattractant
- Interferon-inducible T-cell a chemoattractant I-TAC
- Interferon-inducible T-cell alpha chemoattractant
- IP 9
- IP-9
- IP9
- ITAC
- MGC102770
- SCYB11
- SCYB9B
- Small inducible cytokine B11
- Small inducible cytokine subfamily B (Cys-X-Cys) member 11
- Small inducible cytokine subfamily B (Cys-X-Cys) member 9B
- Small inducible cytokine subfamily B, member 11
- Small inducible cytokine subfamily B, member 9B
- Small-inducible cytokine B11
see all
Function

Chemotactic for interleukin-activated T-cells but not unstimulated T-cells, neutrophils or monocytes. Induces calcium release in activated T-cells. Binds to CXCR3. May play an important role in CNS diseases which involve T-cell recruitment. May play a role in skin immune responses.
Tissue specificity

High levels in peripheral blood leukocytes, pancreas and liver astrocytes. Moderate levels in thymus, spleen and lung. Low levels in placenta, prostate and small intestine. Also found in epidermal basal layer keratinocytes in skin disorders.
Sequence similarities

Belongs to the intercrine alpha (chemokine CxC) family.
Cellular localization

Secreted.
Target information above from: UniProt accession O14625 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

Datasheet

Publishing research using ab9956? Please let us know so that we can cite the reference in this datasheet.

ab9956 has not yet been referenced specifically in any publications.

Stability and Storage

Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

This product is an active protein and may elicit a biological response in vivo, handle with caution.
Reconstitution

For lot specific reconstitution information please contact our Scientific Support Team.