• Product name

  Recombinant Human Claudin18 protein

• Expression system

  Wheat germ

• Protein length

  Full length protein

• Animal free

  No

• Nature

  Recombinant

• • Species

    Human

  • Sequence

    MSTTTCQVVAFLLSILGLAGCIAATGMDMWSTQDLYDNPVTSVFQYEGLW RSCVRQSSGFTECRPYFTILGLPAMLQAVRALMIVGIVLGAIGLLVSIFA LKCIRIGSMEDSAKANMTLTSGIMFIVSGLCAIAGVSVFANMLVTNFWMS TANMYTGMGGMVQTVQTRYTFGAALFVGWVAGGLTLIGGVMMCIACRGLA PEETNYKAVSYHASGHSVAYKPGGFKASTGFGSNTKNKKIYDGGARTEDE VQSYPSKHDYV

  • Amino acids

    1 to 261

  • Tags

    GST tag N-Terminus

• Alternative names

  • Claudin 18
  • Claudin-18
  • CLD18_HUMAN

  • CLDN18
  • SFTA5
  • SFTPJ

  see all

• Function

  Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

• Tissue specificity

  Concentrated at the cell-cell borders of epithelial cells.

• Sequence similarities

  Belongs to the claudin family.

• Cellular localization

  Cell junction > tight junction. Cell membrane.

• Target information above from: UniProt accession P56856 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt