Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant human CD272/BTLA protein (Active) (ab214139)

Key features and details

  • Expression system: CHO cells
  • Purity: >= 98% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: Functional Studies, SDS-PAGE

Description

  • Product name

    Recombinant human CD272/BTLA protein (Active)
    See all CD272/BTLA proteins and peptides

  • Biological activity

    Measured in a competitive binding assay.

  • Purity

    >= 98 % SDS-PAGE.

  • Endotoxin level

  • Expression system

    CHO cells

  • Accession

    Q7Z6A9

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      KESCDVQLYIKRQSEHSILAGDPFELECPVKYCANRPHVTWCKLNGTTCV KLEDRQTSWKEEKNISFFILHFEPVLPNDNGSYRCSANFQSNLIESHSTT LYVTDVKSASERPSKDEMASRPWLLYR

    • Predicted molecular weight

      33 kDa

    • Amino acids

      31 to 157

    • Additional sequence information

      The extracellular domain is fused to the N erminus of the Fc region of Human IgG1. NP_861445.3

    • Specifications

    Our Abpromise guarantee covers the use of ab214139 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    • Applications

      Functional Studies

      SDS-PAGE

    • Form

      Lyophilized

    • Additional notes

       This product was previously labelled as CD272

       

    • Concentration information loading...

    Preparation and Storage

    • Stability and Storage

      Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

      Constituent: 99% PBS

      Lyophilized from 0.2µm-filtered solution.

      This product is an active protein and may elicit a biological response in vivo, handle with caution.

    • Reconstitution
      Reconstitute with 100 µl sterile water. Add 1X PBS to the desired protein concentration.

    General Info

    • Alternative names

      • B and T lymphocyte associated protein
      • B and T lymphocyte attenuator
      • B and T lymphocyte associated
      • B- and T-lymphocyte attenuator
      • B- and T-lymphocyte-associated protein
      • BTLA
      • BTLA_HUMAN
      • BTLA1
      • CD272
      • CD272 antigen
      • FLJ16065
      • MGC129743
      see all

    • Function

      Lymphocyte inhibitory receptor which inhibits lymphocytes during immune response.

    • Sequence similarities

      Contains 1 Ig-like V-type (immunoglobulin-like) domain.

    • Post-translational
      modifications

      Phosphorylated on Tyr residues by TNFRSF14 and by antigen receptors cross-linking, both inducing association with PTPN6 and PTPN11.
      N-glycosylated.

    • Cellular localization

      Membrane.
    • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (0)

Publishing research using ab214139? Please let us know so that we can cite the reference in this datasheet.

ab214139 has not yet been referenced specifically in any publications.

Preparation and Storage

  • B and T lymphocyte associated protein
  • B and T lymphocyte attenuator
  • B and T lymphocyte associated

Images

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