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Recombinant Human CD16 protein (ab151819)

Key features and details

  • Expression system: HEK 293 cells
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Tags: His tag C-Terminus
  • Suitable for: SDS-PAGE, HPLC

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    pH: 7.4
    Constituents: 99% Phosphate Buffer, 0.88% Sodium chloride

  • Reconstitution
    Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Reconstituted protein solution can be stored at 4-7°C for 2-7 days. Aliquots of reconstituted samples are stable at

    General Info

    • Alternative names

      • CD 16
      • CD 16a
      • CD16
      • CD16a
      • CD16a antigen
      • CD16B
      • CD16b antigen
      • Fc fragment of IgG
      • Fc fragment of IgG low affinity IIIa receptor
      • Fc fragment of IgG low affinity IIIa receptor (CD16)
      • Fc fragment of IgG receptor IIIa
      • Fc fragment of IgG, low affinity III, receptor (CD16)
      • Fc fragment of IgG, low affinity III, receptor for (CD16)
      • Fc fragment of IgG, low affinity IIIa, receptor (CD16)
      • Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
      • Fc fragment of IgG, low affinity IIIa, receptor for
      • Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
      • Fc fragment of IgG, low affinity IIIb, receptor for (CD16)
      • Fc gamma R3
      • Fc gamma receptor III 2 (CD 16)
      • Fc gamma receptor III A
      • Fc gamma receptor IIIA
      • Fc gamma receptor IIIb (CD 16)
      • Fc gamma RIII
      • Fc gamma RIII alpha
      • Fc gamma RIII beta
      • Fc gamma RIIIa
      • Fc gamma RIIIb
      • Fc of IgG
      • Fc-gamma receptor III2 (CD 16)
      • Fc-gamma receptor III2 (CD16)
      • Fc-gamma receptor IIIb (CD16)
      • Fc-gamma RIII
      • Fc-gamma RIII-alpha
      • Fc-gamma RIIIa
      • FCG 3
      • FCG3
      • FCG3A_HUMAN
      • FCgammaRIIIA
      • FCGR 3
      • FCGR 3A
      • FCGR3
      • FCGR3A
      • FCGR3A protein
      • FCGRIII
      • FCGRIII-2
      • FcR 10
      • FcR-10
      • FcR10
      • FcRIII
      • FcRIIIa
      • IGFR 3
      • IGFR3
      • IgG Fc receptor III 1
      • IgG Fc receptor III 2
      • IgG Fc receptor III-2
      • IMD20
      • immunoglobulin G Fc receptor III
      • immunoglobulin G Fc receptor III-2
      • Low affinity IIIa receptor
      • Low affinity immunoglobulin gamma Fc region receptor III A
      • Low affinity immunoglobulin gamma Fc region receptor III-A
      • Low affinity immunoglobulin gamma Fc region receptor IIIB
      • neutrophil-specific antigen NA
      see all

    • Function

      Receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis.

    • Tissue specificity

      Expressed on natural killer cells, macrophages, subpopulation of T-cells, immature thymocytes and placental trophoblasts.

    • Sequence similarities

      Contains 2 Ig-like C2-type (immunoglobulin-like) domains.

    • Post-translational
      modifications

      Glycosylated. Contains high mannose- and complex-type oligosaccharides.
      The soluble form is produced by a proteolytic cleavage.

    • Cellular localization

      Cell membrane. Secreted. Exists also as a soluble receptor.
    • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

References (0)

Publishing research using ab151819? Please let us know so that we can cite the reference in this datasheet.

ab151819 has not yet been referenced specifically in any publications.

Images

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