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Immunology Innate Immunity Chemokines Beta Chemokines (CC)

Recombinant Human CCL28/MEC protein (ab50075)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE, Functional Studies

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Description

  • Product name

    Recombinant Human CCL28/MEC protein
    See all CCL28/MEC proteins and peptides
  • Purity

    > 95 % SDS-PAGE.
    ab50075 was estimated also by HPLC. Endotoxin level is less than 0.1 ng per µg (1EU/µg).
  • Endotoxin level

  • Expression system

    Escherichia coli
  • Protein length

    Full length protein
  • Animal free

    No
  • Nature

    Recombinant
    • Species

      Human
    • Sequence

      SEAILPIASS CCTEVSHHIS RRLLERVNMC RIQRADGDCD LAAVILHVKR RRICVSPHNH TVKQWMKVQA AKKNGKGNVC HRKKHHGKRN SNRAHQGKHE TYGHKTPY
    • Amino acids

      1 to 108
  • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab50075 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

        Functional Studies

      • Form

        Lyophilized
      • Additional notes

         This product was previously labelled as CCL28

         

      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

      • Reconstitution
        Reconstitute to 1mg/ml with distilled water.

      General Info

      • Alternative names

        • C C motif chemokine ligand 28
        • C-C motif chemokine 28
        • CC chemokine CCL28
        • CCK 1
        • CCK1
        • CCK1 protein
        • CCL 28
        • CCL28
        • CCL28_HUMAN
        • Chemokine (C-C motif) ligand 28
        • chemokine (C-C motif) ligand 28 splice variant chi
        • MEC
        • Mucosae associated epithelial chemokine
        • Mucosae-associated epithelial chemokine
        • Protein CCK1
        • SCYA28
        • Small inducible cytokine A28 [Precursor]
        • small inducible cytokine subfamily A (Cys-Cys), member 28
        • Small-inducible cytokine A28
        see all
      • Function

        Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.
      • Tissue specificity

        Preferentially expressed by epithelial cells of diverse tissues including normal and pathological colon, salivary gland, mammary gland, trachea and rectum. Also found in prostate, spleen, thyroid, psoriasis skin and in lower levels in peripheral blood leukocytes, small intestine, Peyer patches, stomach and normal skin.
      • Sequence similarities

        Belongs to the intercrine beta (chemokine CC) family.
      • Cellular localization

        Secreted.
      • Target information above from: UniProt accession Q9NRJ3 The UniProt Consortium
        The Universal Protein Resource (UniProt) in 2010
        Nucleic Acids Res. 38:D142-D148 (2010) .

        Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    Datasheets and documents

    • Datasheet
  • References (0)

    Publishing research using ab50075? Please let us know so that we can cite the reference in this datasheet.

    ab50075 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • C C motif chemokine ligand 28
      • C-C motif chemokine 28
      • CC chemokine CCL28
      • CCK 1
      • CCK1
      • CCK1 protein
      • CCL 28
      • CCL28
      • CCL28_HUMAN
      • Chemokine (C-C motif) ligand 28
      • chemokine (C-C motif) ligand 28 splice variant chi
      • MEC
      • Mucosae associated epithelial chemokine
      • Mucosae-associated epithelial chemokine
      • Protein CCK1
      • SCYA28
      • Small inducible cytokine A28 [Precursor]
      • small inducible cytokine subfamily A (Cys-Cys), member 28
      • Small-inducible cytokine A28
      see all
    • Function

      Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.
    • Tissue specificity

      Preferentially expressed by epithelial cells of diverse tissues including normal and pathological colon, salivary gland, mammary gland, trachea and rectum. Also found in prostate, spleen, thyroid, psoriasis skin and in lower levels in peripheral blood leukocytes, small intestine, Peyer patches, stomach and normal skin.
    • Sequence similarities

      Belongs to the intercrine beta (chemokine CC) family.
    • Cellular localization

      Secreted.
    • Target information above from: UniProt accession Q9NRJ3 The UniProt Consortium
      The Universal Protein Resource (UniProt) in 2010
      Nucleic Acids Res. 38:D142-D148 (2010) .

      Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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