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Recombinant human CCL28/MEC protein (ab202812)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 97% SDS-PAGE
  • Endotoxin level:
  • Active: Yes
  • Suitable for: HPLC, SDS-PAGE, Functional Studies

Preparation and Storage

  • Alternative names

    • C C motif chemokine ligand 28
    • C-C motif chemokine 28
    • CC chemokine CCL28
    • CCK 1
    • CCK1
    • CCK1 protein
    • CCL 28
    • CCL28
    • CCL28_HUMAN
    • Chemokine (C-C motif) ligand 28
    • chemokine (C-C motif) ligand 28 splice variant chi
    • MEC
    • Mucosae associated epithelial chemokine
    • Mucosae-associated epithelial chemokine
    • Protein CCK1
    • SCYA28
    • Small inducible cytokine A28 [Precursor]
    • small inducible cytokine subfamily A (Cys-Cys), member 28
    • Small-inducible cytokine A28
    see all

  • Function

    Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.

  • Tissue specificity

    Preferentially expressed by epithelial cells of diverse tissues including normal and pathological colon, salivary gland, mammary gland, trachea and rectum. Also found in prostate, spleen, thyroid, psoriasis skin and in lower levels in peripheral blood leukocytes, small intestine, Peyer patches, stomach and normal skin.

  • Sequence similarities

    Belongs to the intercrine beta (chemokine CC) family.

  • Cellular localization

    Secreted.
  • Information by UniProt

Images

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