Antibodies, Proteins, Kits and Reagents for Life Science

Key features and details

Expression system: Escherichia coli
Purity: > 97% SDS-PAGE
Endotoxin level:
Active: Yes
Suitable for: HPLC, SDS-PAGE, Functional Studies

Alternative names
- C C motif chemokine ligand 28
- C-C motif chemokine 28
- CC chemokine CCL28
- CCK 1
- CCK1
- CCK1 protein
- CCL 28
- CCL28
- CCL28_HUMAN
- Chemokine (C-C motif) ligand 28
- chemokine (C-C motif) ligand 28 splice variant chi
- MEC
- Mucosae associated epithelial chemokine
- Mucosae-associated epithelial chemokine
- Protein CCK1
- SCYA28
- Small inducible cytokine A28 [Precursor]
- small inducible cytokine subfamily A (Cys-Cys), member 28
- Small-inducible cytokine A28
see all
Function

Chemotactic activity for resting CD4, CD8 T-cells and eosinophils. Binds to CCR3 and CCR10 and induces calcium mobilization in a dose-dependent manner.
Tissue specificity

Preferentially expressed by epithelial cells of diverse tissues including normal and pathological colon, salivary gland, mammary gland, trachea and rectum. Also found in prostate, spleen, thyroid, psoriasis skin and in lower levels in peripheral blood leukocytes, small intestine, Peyer patches, stomach and normal skin.
Sequence similarities

Belongs to the intercrine beta (chemokine CC) family.
Cellular localization

Secreted.
Target information above from: UniProt accession Q9NRJ3 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

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