Recombinant human CCL25 protein (ab586)
Key features and details
- Expression system: Escherichia coli
- Purity: > 98% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
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Product name
Recombinant human CCL25 protein
See all CCL25 proteins and peptides -
Biological activity
Determined by its ability to bind CCR9 receptor expressed on the surface of MOLT4 cells.
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Purity
> 98 % SDS-PAGE.
Sterile filtered. Greater than 98% pure by SDS-PAGE and HPLC analyses. Endotoxin level is less than 0.1 ng per µg (1EU/µg). -
Expression system
Escherichia coli -
Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Human -
Sequence
hTECK is a 14.2 kDa protein containing 127 amino acid residues: QGVFEDCCLA YHYPIGWAVL RRAWTYRIQE VSGSCNLPAA IFYLPKRHRK VCGNP KSREVQRAMKLLDAR NKVFAKLHHN MQTFQAGPHA VKKLSSGNSK L SSSKFSNPI SSSRKNVSLLISANSGL
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Preparation and Storage
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Alternative names
- A130072A22Rik
- C-C motif chemokine 25
- CCL 25
see all -
Function
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. -
Tissue specificity
Specifically expressed by thymic dendritic cells. High levels in thymus and small intestine. -
Sequence similarities
Belongs to the intercrine beta (chemokine CC) family. -
Cellular localization
Secreted. - Information by UniProt
