Recombinant human CCL21 protein (Active) (ab268385)
Key features and details
- Expression system: Escherichia coli
- Purity: >= 95% SDS-PAGE
- Endotoxin level:
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
Preparation and Storage
-
Alternative names
- 6Ckine
- Beta chemokine exodus 2
- Beta-chemokine exodus-2
see all -
Function
Inhibits hemopoiesis and stimulates chemotaxis. Chemotactic in vitro for thymocytes and activated T-cells, but not for B-cells, macrophages, or neutrophils. Shows preferential activity towards naive T-cells. May play a role in mediating homing of lymphocytes to secondary lymphoid organs. -
Tissue specificity
Highly expressed in high endothelial venules of lymph nodes, spleen and appendix. Intermediate levels found in small intestine, thyroid gland and trachea. Low level expression in thymus, bone marrow, liver, and pancreas. Also found in tonsil, fetal heart and fetal spleen. -
Sequence similarities
Belongs to the intercrine beta (chemokine CC) family. -
Cellular localization
Secreted. - Information by UniProt
Images
-
Functional Studies - Recombinant human CCL21 protein (Active) (ab268385)
The specific activity of ab268385 was determined by its ability to chemoattract total lymphocyte population using a concentration range of 10-100 ng/ml.
-
SDS-PAGE - Recombinant human CCL21 protein (Active) (ab268385)SDS-PAGE analysis of ab268385.
