Astana Biomed Group, an authorized Abcam distributor in Central Asia

Recombinant Human BCMA protein (ab50089)

Key features and details

  • Expression system: Escherichia coli
  • Purity: > 95% SDS-PAGE
  • Endotoxin level:
  • Suitable for: SDS-PAGE

Description

  • Product name

    Recombinant Human BCMA protein
    See all BCMA proteins and peptides

  • Purity

    > 95 % SDS-PAGE.
    ab50089 purity was evaluated also by HPLC. Endotoxin level is less than 0.1 ng per µg (1EU/µg).

  • Endotoxin level

  • Expression system

    Escherichia coli

  • Protein length

    Protein fragment

  • Animal free

    No

  • Nature

    Recombinant

    • Species

      Human

    • Sequence

      AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA

    • Amino acids

      5 to 54

    • Associated products

      Specifications

      Our Abpromise guarantee covers the use of ab50089 in the following tested applications.

      The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

      • Applications

        SDS-PAGE

      • Form

        Lyophilized
      • Concentration information loading...

      Preparation and Storage

      • Stability and Storage

        Shipped at 4°C. The lyophilized protein is stable for a few weeks at room temperature. Store at -20°C long term.

      • Reconstitution
        Reconstitute to 1mg/ml with distilled water.

      General Info

      • Alternative names

        • B cell maturation antigen
        • B cell maturation factor
        • B cell maturation protein
        • B-cell maturation protein
        • BCM
        • BCMA
        • CD269
        • CD269 antigen
        • TNFRSF17
        • TNR17_HUMAN
        • Tumor necrosis factor receptor superfamily member 17
        see all

      • Function

        Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.

      • Tissue specificity

        Expressed in mature B-cells, but not in T-cells or monocytes.

      • Involvement in disease

        Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.

      • Sequence similarities

        Contains 1 TNFR-Cys repeat.

      • Cellular localization

        Cell membrane. Endomembrane system. Perinuclear Golgi-like structures.
      • Information by UniProt

    Protocols

    To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

    Click here to view the general protocols

    References (0)

    Publishing research using ab50089? Please let us know so that we can cite the reference in this datasheet.

    ab50089 has not yet been referenced specifically in any publications.

    Preparation and Storage

    • Alternative names

      • B cell maturation antigen
      • B cell maturation factor
      • B cell maturation protein
      • B-cell maturation protein
      • BCM
      • BCMA
      • CD269
      • CD269 antigen
      • TNFRSF17
      • TNR17_HUMAN
      • Tumor necrosis factor receptor superfamily member 17
      see all

    • Function

      Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK.

    • Tissue specificity

      Expressed in mature B-cells, but not in T-cells or monocytes.

    • Involvement in disease

      Note=A chromosomal aberration involving TNFRSF17 is found in a form of T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(4;16)(q26;p13) with IL2.

    • Sequence similarities

      Contains 1 TNFR-Cys repeat.

    • Cellular localization

      Cell membrane. Endomembrane system. Perinuclear Golgi-like structures.
    • Information by UniProt

    Images

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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