Antibodies, Proteins, Kits and Reagents for Life Science

Recombinant human Amphiregulin protein (Active) (ab229600)

Key features and details

Expression system: Escherichia coli
Purity: >= 95% SDS-PAGE
Endotoxin level:
Active: Yes
Suitable for: Functional Studies, SDS-PAGE

Alternative names
- A REG
- Amphiregulin
- Amphiregulin B
- AR
- AREG
- AREG_HUMAN
- AREGB
- Colorectum cell derived growth factor
- Colorectum cell-derived growth factor
- CRDGF
- MGC13647
- Schwannoma derived growth factor
- SDGF
see all
Function

Bifunctional growth-modulating glycoprotein. Inhibits growth of several human carcinoma cells in culture and stimulates proliferation of human fibroblasts and certain other tumor cells.
Sequence similarities

Belongs to the amphiregulin family.
Contains 1 EGF-like domain.
Cellular localization

Membrane.
Target information above from: UniProt accession P15514 The UniProt Consortium
The Universal Protein Resource (UniProt) in 2010
Nucleic Acids Res. 38:D142-D148 (2010) .

Information by UniProt

Functional Studies - Recombinant human Amphiregulin protein (Active) (ab229600)

ab229600 induced proliferation of 3T3 cells.
SDS-PAGE - Recombinant human Amphiregulin protein (Active) (ab229600)

1 µg ab229600 analyzed on a 4-20% Tris-Glycine gel, stained with Coomassie Blue.

Lane 1: Non-reducing conditions.

Lane 2: Reducing conditions.

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