Recombinant chicken IL-10 protein (Active) (ab87526)
Key features and details
- Expression system: Yeast
- Purity: > 95% SDS-PAGE
- Active: Yes
- Suitable for: Functional Studies, SDS-PAGE
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Product name
Recombinant chicken IL-10 protein (Active)
See all IL-10 proteins and peptides -
Biological activity
The biological activity of recombinant chicken IL-10 was determined by measuring IFN-gamma expression by RTPCR in Concanavalin A-stimulated chicken spleen lymphocytes. Results demonstrate decreased IFN-gamma gene expression, with the addition of recombinant chicken IL-10, in a dose dependant manner, with doses starting at 2 ng/ml.
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Purity
> 95 % SDS-PAGE.
ab87526 is purified by Ion-exchange chromatography. -
Expression system
Yeast -
Accession
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Protein length
Full length protein -
Animal free
No -
Nature
Recombinant -
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Species
Chicken -
Sequence
LEPTCLHFSELLPARLRELRVKFEEIKDYFQSRDDELNIQLLSSELLDKF KGTFGCQSVSEMLRFYTDEVLPRAMQTSTSHQQSMGDLGNMLLGLKATMR RCHRFFTCEKRSKAIKQIKETFEKMDENGIYKAMGEFDIFINYIEEYLLM RRRK -
Predicted molecular weight
18 kDa -
Amino acids
22 to 175 -
Additional sequence information
This product is for the mature full length protein. The signal peptide is not included.
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Preparation and Storage
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Alternative names
- CSIF
- Cytokine synthesis inhibitory factor
- GVHDS
see all -
Function
Inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF produced by activated macrophages and by helper T-cells. -
Tissue specificity
Produced by a variety of cell lines, including T-cells, macrophages, mast cells and other cell types. -
Sequence similarities
Belongs to the IL-10 family. -
Cellular localization
Secreted. - Information by UniProt
