Rat Prolactin R ELISA Kit (PRLR) (ab113351)
Key features and details
- Sensitivity: 0.4 ng/ml
- Range: 0.512 ng/ml - 50 ng/ml
- Sample type: Cell culture supernatant
- Detection method: Colorimetric
- Assay type: Sandwich (quantitative)
- Reacts with: Rat
Properties
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Storage instructions
Store at -20°C. Please refer to protocols. -
Components 1 x 96 tests 20X Wash Buffer Concentrate 1 x 25ml 400X HRP-Streptavidin Concentrate 1 x 200µl 5X Assay Diluent B 1 x 15ml 5X Assay Diluent D 1 x 15ml Biotinylated anti-rat Prolactin R 2 vials Prolactin R Microplate (12 x 8 wells) 1 unit Recombinant rat Prolactin R Standard (lyophilized) 2 vials Stop Solution 1 x 8ml TMB One-Step Substrate Reagent 1 x 12ml -
Research areas
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Function
This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. -
Tissue specificity
Expressed in breast, placenta, kidney, liver and pancreas. -
Sequence similarities
Belongs to the type I cytokine receptor family. Type 1 subfamily.
Contains 2 fibronectin type-III domains. -
Domain
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation. -
Cellular localization
Secreted and Membrane. - Information by UniProt
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Alternative names
- AI987712
- CLONE SPM213
- CPRLP
see all -
Database links
- Entrez Gene: 24684 Rat
- SwissProt: P05710 Rat
- Unigene: 9757 Rat
Images
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Typical data
Representative standard curve using ab113351
