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Signal Transduction Signaling Pathway G Protein Signaling Small G Proteins Other

Rat NT-ProANP Antibody Pair - BSA and Azide free (ab270360)

Price and availability

670 ₸

Availability

Order now and get it on Friday March 05, 2021

Rat NT-ProANP Antibody Pair - BSA and Azide free (ab270360)
  • ChIP - Anti-Histone H3 antibody - Nuclear Loading Control and ChIP Grade (ab1791)

Key features and details

  • Unconjugated capture and detector antibodies
  • Adaptable to any antibody pair-based assay format
  • Antibody concentration ~ 1 mg/ml
  • BSA and azide free buffer - ready for conjugation
  • Reacts with: Rat

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Overview

  • Product name

    Rat NT-ProANP Antibody Pair - BSA and Azide free
    See all proANP kits
  • Assay type

    ELISA set
  • Range

    62.5 pg/ml - 4000 pg/ml
  • Species reactivity

    Reacts with: Rat
  • Product overview

    The Antibody Pair can be used to quantify Rat NT-ProANP. BSA and Azide free antibody pairs include unconjugated capture and detector antibodies suitable for sandwich ELISAs. The antibodies are provided at an approximate concentration of 1 mg/ml as measured by the protein A280 method. The recommended antibody orientation is based on internal optimization for ELISA-based assays. Antibody orientation is assay dependent and needs to be optimized for each assay type. Both capture and detector antibodies are rabbit monoclonal antibodies delivering consistent, specific, and sensitive results.


    For additional information on the performance of the antibody pair, see the equivalent SimpleStep ELISA® Kit (ab267803), which uses the same antibodies. However, due to differences in their formulation, this antibody pair cannot be used with the consumables provided with our SimpleStep ELISA Kits. Please note that the range provided for the pairs is only an estimation based on the performance of the related product using the same antibody pair. Performance of the antibody pair will depend on the specific characteristics of your assay. We guarantee the product works in sandwich ELISA, but we do not guarantee the sensitivity or dynamic range of the antibody pair in your assay.


    Download SDS here.

  • Tested applications

    Suitable for: Sandwich ELISAmore details
  • Platform

    Reagents

Properties

  • Storage instructions

    Store at +4°C. Please refer to protocols.
  • Carrier free

    Yes
  • Components 10 x 96 tests
    Rat NT-ProANP Capture Antibody (unconjugated) 1 x 100µg
    Rat NT-ProANP Detector Antibody (unconjugated) 1 x 100µg
  • Research areas

    • Cardiovascular
    • Blood
    • Other
    • Cardiovascular
    • Blood
    • Blood Pressure regulation
    • Cardiovascular
    • Heart
    • Hypertrophy
    • Hormones
    • Cardiovascular
    • Heart
    • Hypertrophy
    • Other
  • Function

    Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Also plays a role in female pregnancy by promoting trophoblast invasion and spiral artery remodeling in uterus. Specifically binds and stimulates the cGMP production of the NPR1 receptor. Binds the clearance receptor NPR3.
  • Involvement in disease

    Atrial standstill 2
    Atrial fibrillation, familial, 6
  • Sequence similarities

    Belongs to the natriuretic peptide family.
  • Post-translational
    modifications

    Cleaved by CORIN upon secretion to produce the functional hormone.
    Atrial natriuretic factor: Cleaved by MME. The cleavage initiates degradation of the factor and thereby regulate its activity.
  • Cellular localization

    Secreted.
  • Target information above from: UniProt accession P01160 The UniProt Consortium
    The Universal Protein Resource (UniProt) in 2010
    Nucleic Acids Res. 38:D142-D148 (2010) .

    Information by UniProt
  • Alternative names

    • ANF
    • ANF_HUMAN
    • ANP
    • ATFB6
    • Atrial natriuretic factor
    • Atrial natriuretic peptide
    • Atriopeptin
    • ATRST2
    • Cardiodilatin
    • Cardiodilatin-related peptide
    • Cardionatrin
    • CDD
    • CDD ANF
    • CDD-ANF
    • CDP
    • Natriuretic peptide A
    • Natriuretic peptide precursor A
    • Natriuretic peptides A
    • NPPA
    • PND
    • Prepronatriodilatin
    • Pronatriodilatin
    see all
  • Database links

    • Entrez Gene: 24602 Rat
    • SwissProt: P01161 Rat
    • Unigene: 2004 Rat

    Images

    • Sandwich ELISA - Rat NT-ProANP Antibody Pair - BSA and Azide free (ab270360)
      Sandwich ELISA - Rat NT-ProANP Antibody Pair - BSA and Azide free (ab270360)
      To learn more about the advantages of recombinant antibodies see here.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
    For licensing inquiries, please contact partnerships@abcam.com

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