• Product name

  RAP1GAP peptide

• Animal free

  No

• Nature

  Synthetic

• Alternative names

  • KIAA0474
  • RAP1 GTPase activating protein
  • Rap1 GTPase activating protein 1

  • Rap1 GTPase-activating protein 1
  • RAP1GA1
  • Rap1ga1 protein
  • Rap1GAP
  • Rap1GAP1
  • RAP1GAPII
  • RAPGAP
  • RPGP1_HUMAN

  see all

• Function

  GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.

• Tissue specificity

  Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues.

• Sequence similarities

  Contains 1 GoLoco domain.
  Contains 1 Rap-GAP domain.

• Cellular localization

  Golgi apparatus membrane.

• Target information above from: UniProt accession P47736 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt