Ramosetron, 5-HT3 receptor antagonist (ab142537)
Key features and details
- Highly potent, selective 5-HT3 receptor antagonist
- CAS Number: 132036-88-5
- Purity: > 98%
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Ramosetron, 5-HT3 receptor antagonist -
Description
Highly potent, selective 5-HT3 receptor antagonist -
Biological description
Highly potent, selective 5-HT3 receptor antagonist (Ki values are 91 and 220 pM at human and rat receptors respectively). Shows antiemetic and anti-diarrhoeal effects in vivo. Orally active. Partially blood-brain barrier permeable. -
Purity
> 98% -
CAS Number
132036-88-5 -
Chemical structure
Properties
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Chemical name
(1-Methylindol-3-yl)-[(5R)-4,5,6,7-tetrahydro-3H-benzimidazol-5-yl]methanone -
Molecular weight
279.34 -
Molecular formula
C17H17N3O -
PubChem identifier
108000 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN1C=C(C2=CC=CC=C21)C(=O)C3CCC4=C(C3)NC=N4 -
Source
Synthetic
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Research areas
