R-(+)-Cotinine, chiral primary nicotine metabolite (ab144738)
Key features and details
- Chiral primary nicotine metabolite. Neuronal nAChR agonist.
- CAS Number: 32162-64-4
- Soluble in water and in ethanol
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
R-(+)-Cotinine, chiral primary nicotine metabolite -
Description
Chiral primary nicotine metabolite. Neuronal nAChR agonist. -
Biological description
Chiral primary nicotine (ab145110, ab145013, ab120562, ab120450) metabolite. Neuronal nAChR agonist. Shows a much longer half life of 20 hours than nicotine. Shows carcinogenic effects. Improves sustained attention and decreasing impulsive and compulsive behaviours. Shows antipsychotic effects in vivo. Blood-brain barrier permeable. -
CAS Number
32162-64-4 -
Chemical structure
Properties
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Chemical name
(5R)-1-Methyl-5-(pyridin-3-yl)pyrrolidin-2-one -
Molecular weight
176.22 -
Molecular formula
C10H12N2O -
PubChem identifier
21907 -
Storage instructions
Store at -20°C. Store In the Dark. This product is air and light sensitive and impurities can occur as a result of air oxidation or due to metabolism by microbes. -
Solubility overview
Soluble in water and in ethanol -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CN1[C@H](CCC1=O)C2=CN=CC=C2 -
Source
Synthetic
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Research areas
