R-(-)-alpha-Methylhistamine dihydrobromide, H3 receptor agonist (ab120774)
Key features and details
- Highly potent, selective H3 receptor agonist
- CAS Number: 75614-87-8
- Purity: > 99%
- Soluble in water to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
R-(-)-alpha-Methylhistamine dihydrobromide, H3 receptor agonist -
Description
Highly potent, selective H3 receptor agonist -
Biological description
Highly potent, selective H3 receptor agonist (Kd = 50 nM). Induces H4-mediated eosinophil shape change (EC50 = 66 nM). Inhibits H3-mediated histamine synthesis and release in the CNS. Active in vivo. -
Purity
> 99% -
CAS Number
75614-87-8 -
Chemical structure
Properties
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Chemical name
1-(1H-Imidazol-5-yl)propan-2-amine dihydrobromide -
Molecular weight
287.00 -
Molecular formula
C6H11N3.2HBr -
PubChem identifier
206868 -
Storage instructions
Store at Room Temperature. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC(CC1=CN=CN1)N.Br.Br -
Source
Synthetic
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Research areas