Melittin, apoptotic agent (ab143517)
Key features and details
- Cationic antimicrobial peptide. Membrane-disruptive and apoptotic agent.
- CAS Number: 20449-79-0
- Purity: > 98%
- Soluble in water (5mg/mL)
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Melittin, apoptotic agent -
Description
Cationic antimicrobial peptide. Membrane-disruptive and apoptotic agent. -
Biological description
Cationic antimicrobial peptide. Membrane-disruptive and apoptotic agent. Induces surface-tension disruption and cell lysis. Induces ROS-mediated apoptosis. Induces histamine release. Stimulates muscle contractility and shows antifungal effects in vivo. -
Purity
> 98% -
CAS Number
20449-79-0 -
Chemical structure
Properties
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Molecular weight
2846.50 -
Molecular formula
C131H229N39O31 -
Sequence
GIGAVLKVLTTGLPALISWIKRKRQQ (Modifications: C-terminal amide) -
PubChem identifier
16133648 -
Storage instructions
Store at +4°C. The product can be stored for up to 12 months. -
Solubility overview
Soluble in water (5mg/mL) -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Toxic, refer to SDS for further information.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CCC(C)C(C(=O)NCC(=O)NC(C)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCCN)C(=O)NC(C(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)O)C(=O)NC(C(C)O)C(=O)NCC(=O)NC(CC(C)C)C(=O)N1CCCC1C(=O)NC(C)C(=O)NC(CC(C)C)C(=O)NC(C(C)CC)C(=O)NC(CO)C(=O)NC(CC2=CNC3=CC=CC=C32)C(=O)NC(C(C)CC)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)N)NC(=O)CN -
Source
Synthetic
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Research areas
