Quinol 2, Antitumor agent (ab144640)
Key features and details
- Selective antitumor agent. Thioredoxin reductase inhibitor.
- CAS Number: 485842-97-5
- Purity: > 99%
- Soluble in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
Overview
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Product name
Quinol 2, Antitumor agent -
Description
Selective antitumor agent. Thioredoxin reductase inhibitor. -
Biological description
Selective antitumor agent. Active against colon, renal and breast carcinomas in vitro and ex vivo. Inhibits thioredoxin reductase with potencies correlated with antiproliferative and cytotoxic effects. Potent inhibitory effect in NCI 60 cells (GI50 =0.23 µM and LC50 = 3.39 µM).
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Purity
> 99% -
General notes
Sold under license from CRT -
CAS Number
485842-97-5 -
Chemical structure
Properties
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Chemical name
4-(1,3-Benzothiazol-2-yl)-4-hydroxycyclohexa-2,5-dien-1-one -
Molecular weight
243.28 -
Molecular formula
C13H9NO2S -
PubChem identifier
482697 -
Storage instructions
Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months. -
Solubility overview
Soluble in ethanol to 100 mM and in DMSO to 100 mM -
Handling
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
O=C1C=CC(O)(C=C1)c2nc3ccccc3s2 -
Source
Synthetic
